In 225 clinical scenarios based on Choosing Wisely recommendations, LLMs aligned with evidence-based guidance, recommending potentially unnecessary tests or treatments in just 5.4% of responses and rarely withholding appropriate care. Researchers found that LLMs were more likely to suggest unnecessary care in scenarios where clinical guidance is debated or symptoms could reasonably justify additional testing.   These findings suggest that commercial LLMs generally align with evidence-based principles of medical restraint while highlighting opportunities for targeted improvement. bit.ly/3UevlnQ @deanarielmd @ClalitHealth @GuyLaban @bengurionu

Updated guidance from @goKDIGO recommends a more individualized approach to managing anemia in chronic kidney disease, including tailored treatment decisions, preferred use of IV iron for patients on hemodialysis, and addressing reversible causes before drug therapy. Read a synopsis of the guidelines here: bit.ly/4yhoVDn