Whitehead Institute is a world-renowned, non-profit scientific institution dedicated to improving human health through basic biomedical research.

Cambridge, MA, USA
Joined September 2012
A detailed map of this kind could help scientists pinpoint when things go wrong in birth defects, trace how cancer cells acquire the ability to spread or resist treatment, and better guide stem cells into mature, functional cell types.
Every cell in our body comes from 1 fertilized egg — & now we can trace that dev. #HHMIInvestigators Jonathan Weissman & Jay Shendure & teams have created new tools that generate maps of the origin & outcome of vast numbers of cells in a developing mouse: bit.ly/4dVhnhe
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We're bringing hands-on science to @MITMuseum's Cambridge Science Carnival this weekend. We look forward to seeing you there! #cambrigdesciencecarnaval #mitfuturefest #BostonUncovered #funthingstodoboston
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Two Whitehead Institute Members have received Bose Research Grants: Iain Cheeseman will study overlooked versions of known proteins linked to disease, while Siniša Hrvatin will explore how some animals survive freezing to advance cryopreservation. tinyurl.com/5csd3ejj
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Toxoplasma gondii, the parasite that causes toxoplasmosis, can invade a host cell in less than a minute. New research out of Whitehead reveals that Toxoplasma doesn’t simply recognize a ready-made doorway into a cell. Instead, it helps create the conditions its entry.
Breaking and Entering: How #Parasites Prepare Host Cells for Invasion @WhiteheadInst newswise.com/articles/breaki…
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What happens when artificial intelligence (AI) makes its way into the lab? In a new @Nature feature, Whitehead scientists Kalon Overholt and Anna Pertl share how they're using AI as a tool for scientific discovery and why human expertise remains essential: tinyurl.com/mvbzemh2
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Whitehead Institute’s Scientific Advisory Board brings together leading scientists to engage with our researchers and offer outside perspective. Hear more from @HarmitMalik of @fredhutch and @UW about his decision to get involved with Whitehead: tinyurl.com/4pcntm6b
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Messenger RNA carries genetic instructions that make proteins. But all RNA molecules are naturally sticky. Now, Whitehead Institute researchers have discovered one way cells may have evolved to keep them from clumping together. tinyurl.com/4jtsvas3
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Whitehead Institute retweeted
Excited to share our new preprint led by @YiChenNeumann with incredible collaborators @labs_mann, @BenGewurz, @StephenE92884, and @hopfnerlab to characterize the function of thousands of viral microproteins from human-infecting viruses! biorxiv.org/content/10.64898…
Excited to share my PhD work, now on @bioRxiv! 🎓🦠Viruses are packed with small ORFs with unknown function. At @JswLab w/ collaborators, we built a pan-viral microprotein atlas that uncovered the oncogenic activity of BNLF2b, an EBV gene linked to cancer. biorxiv.org/content/10.64898…
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The path from foundational biology research to life-saving therapies is often measured in decades. This year, that journey for one Whitehead discovery reached a remarkable milestone 1/4
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This year, the experimental drug daraxonrasib, which targets Ras-driven cancers, has shown historic progress against pancreatic cancer — one of the deadliest and most difficult cancers to treat. Researchers call it the most significant advance in cancer treatment in 15 years 3/4
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For us, this is a powerful reminder that transformative therapies begin with fundamental discoveries. We're proud to have helped lay the scientific groundwork that made this breakthrough possible 4/4
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“I’ve also really valued the richly collaborative community, and being able to take a lot of risks in how I address the questions I have the opportunity to pursue,” says grad student Giselle Valdes, reflecting on her time at @MIT and Whitehead Institute. tinyurl.com/56hdxshv
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Whitehead Institute retweeted
When I was in college @MITBiology, I worked in the @WhiteheadInst lab of the scientist, Bob Weinberg, who discovered the very first oncogene, ras. Decades later, a drug targeting ras has finally made historic progress in pancreatic cancer. A great moment.
a standing ovation for daraxonrasib at asco. over 40k oncologists, entrepreneurs, investors, and patient advocates together celebrating revmed's breakthru in the fight against pancreatic cancer. u never forget these moments. it's what innovation is all about.
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Whitehead Institute retweeted
Wheat, rice & corn feed the world; #HHMIInvestigator Mary Gehring's lab has built a gene expression “map” of seed development in a plant model that could help improve crops' ability to withstand environmental stress: bit.ly/4u1p62y.
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Crops are facing increasing stress from heat, drought, and poor soil conditions. Now Whitehead researchers have created a gene expression “map” of seed development that could help guide future efforts to improve crop yield, nutrition, and resilience: shorturl.at/CLWq1
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We are deeply saddened by the passing of Brit d’Arbeloff, Director Emerita of the Board and longtime supporter of the Institute. Her legacy is profound and includes advancing our efforts to understand of how sex differences influence health and disease. shorturl.at/byRH5
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