Clinical Computational Oncology @DanaFarber @harvardmed @broadinstitute | Chief AI Officer & PopSci | Prev: @Stanford @UCLA @UCSF | Disc: https://xitter.cf/t.co/EmrHxvg76N
Boston, MA
Joined June 2010
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Eli Van Allen retweeted
We are now accepting applications for the T32 postdoctoral fellowship training program: Training in Oncology Population Sciences (TOPS)
Applications are due 12/16 and accepted fellows will begin their training in September 2027. TOPSPostdoc.org
Eli Van Allen retweeted
In case anyone is running agents and wondering if you can leave them running on a holiday, know that Chabad is on the case!
chabad.org/library/article_c…
Eli Van Allen retweeted
New work from Pasi A. Jänne, us, and 23andme; led by Jackie LoPiccolo and Steven Micheletti. Characterizing a highly penetrant germline founder mutation for lung cancer.
An inherited genetic mutation may increase lung cancer risk among people who have never smoked, according to a new Science study.
By tracing the ancestry of people carrying the rare EGFR T790M variant, researchers uncovered a shared genetic legacy extending back hundreds of years and concentrated in the southeastern United States.
Learn more in this week’s issue: scim.ag/46q1kUC
ALT An inherited mutation in the EGFR gene (EGFR T790M) increases lung cancer risk. In this illustration, lungs merge with a map of the United States, reflecting the geographic enrichment of the EGFR T790M mutation. By tracing the ancestry of people carrying this mutation, researchers uncovered a shared genetic legacy extending back hundreds of years and concentrated in the southeastern United States. Illustration: Oliver Uberti
In our latest, we continued multi-omic exploration of GI neuroendocrine tumors, finding potential organ-specific molecular programs and microenvironmental niches - congrats Julie Karam @SamHoffmanMed et al! @DanaFarber @broadinstitute @jclinicalinvest jci.org/articles/view/204119
Eli Van Allen retweeted
🚨We are hiring! 🚨
The Department of Biostatistics @HarvardChan and the Department of Data Science @DanaFarber are recruiting a tenure-track Assistant/Associate Professor in statistics or machine learning with interests in single-cell or spatial genomics.
Link below 👇
In our latest, we studied how certain immune cells surround bladder tumors and contribute to chemotherapy resistance, pointing to a surprising potential therapeutic target ...
Congrats @CarvalhoFilipeL @mouwlab et al! @CellPressNews @cellpressblue cell.com/cell-press-blue/ful…
Eli Van Allen retweeted
Here's our latest in @cellpressblue. In collaboration with @VanAllenLab and @mouwlab, we asked a simple question:
Why do some muscle-invasive bladder cancers survive neoadjuvant chemotherapy? 🧵cell.com/cell-press-blue/ful…
Congrats to @JihyunkaLee et al!
Eli Van Allen retweeted
Very exciting new method for inferring latent disease trajectories, led by the tireless Dr. Urbut with Natarajan and Parmigiani labs. If you're considering a postdoc in this area talk to Sarah!
One of my first consults as a cardiology fellow: a 34-year-old, textbook MI. A day earlier, no risk model would have flagged him for prevention. That paradox has driven my work ever since — our models miss how disease actually evolves, dynamically, on top of a genetic background. @Nature nature.com/articles/s41586-0…
Eli Van Allen retweeted
One of my first consults as a cardiology fellow: a 34-year-old, textbook MI. A day earlier, no risk model would have flagged him for prevention. That paradox has driven my work ever since — our models miss how disease actually evolves, dynamically, on top of a genetic background. @Nature nature.com/articles/s41586-0…
Eli Van Allen retweeted
Please repost! We are seeking #PostDocs to join our lab in @YaleGenetics @YaleCancer @CancerYale to study #genetic and #host drivers of #PancreaticCancer and #LungCancer. Check out our newly updated website for more lab details! medicine.yale.edu/lab/muzumd…
Eli Van Allen retweeted
📣Delighted to share two new studies from our team
using germline genome sequencing 🧬
to understand #cancer #predisposition!
Interested? 🧵👇 for details
1/15
Eli Van Allen retweeted
Using burgers as a model system, a generative AI system rediscovers the classic Big Mac without explicit supervision and generates novel burgers optimized for deliciousness, sustainability, or nutrition, according to a paper in npj Science of Food. go.nature.com/3SU7JDQ
ALT This is figure 2, which shows rediscovering classic burger and discovering delicious burgers.
Eli Van Allen retweeted
1/ Results from #ARC20 trial are out in @Nature!
This trial evaluated the HIF-2α inhibitor Casdatifan in heavily pretreated advanced ccRCC and provides important insights into HIF-2α biology and response. This is the 2nd HIF2 inhibitor with enough activity to move to a pivotal study after Belzutifan, cementing the 2019 @nobelprize story with @kaelinlab et al
Check it out: nature.com/articles/s41586-0…
In our latest, we tested elements of cancer biology research using @AnthropicAI AI agents, with varying amounts of human involvement across multi-step, multi-omic analyses
Interesting times for agentic AI & biological discovery, and for the future of (cancer) biology research...
... especially since this is currently the worst these technologies will ever be at these (and other) tasks ...
link: biorxiv.org/content/10.64898…
Eli Van Allen retweeted
We are hiring! We are specifically looking for a postgraduate associate - someone who has recently finished university and is ultimately looking to apply to medical school or graduate school.
It is a TWO YEAR clinical/translational position, where you will be interacting closely with patients, involved in translational clinical trials, and working hands on in the lab and with clinical databases.
The ideal candidate is a great communicator, organized, and enthusiastic about patient-oriented clinical and lab research. You will get dedicated mentoring not just on the science and clinic, but also on career/professional development as well.
We are looking for someone to start ASAP! More information here:
postdocs.yale.edu/posts/2026…
Please help to spread the word and RT!
@DrChoueiri @VanAllenLab @tompowles1 @YaleCancer @YaleMed @SmilowCancer @kidneycan @OncoAlert @OncLive @KidneyCancer @A_P_S_A @cure_today @yalepathology @Yale_Urology @DrYukselUrun @MarkDSiegel1 @OncBrothers @DrKarineTawagi
In our latest, a surprise - thanks to computational pathology - about immune cell clustering in prostate cancer and new ways to understand tumors, their neighborhoods, and clinical outcomes ... congrats @DYangMD et al! (link below)
Link to study: aacrjournals.org/clincancerr…
Had fun discussing AI innovations in health care with @TheAtlantic @tgoetz, highlighting work by @kenlkehl @ecerami @DFCIPopSci on AI for clinical trial matching in oncology + other exciting applications of AI across @DanaFarber theatlantic.com/sponsored/li…
Link to the panel: youtube.com/watch?v=rPV9r0xj…
Link to Ken et al's MatchMiner-AI tool: arxiv.org/abs/2412.17228
We are always looking for ways to thoughtfully support of these efforts, reach out for more!