Joined July 2011
Exciting news: two of our @renphilanthropy team have been appointed Venture Directors by the Cabinet Office of Japan. Our ASCENT Japan program supports the Japanese government’s work launching ARPA-style programs to enable scientific and technology breakthroughs, using our Big-if-True Science Accelerator (BiTS) approach to train science leaders capable of designing and implementing ambitious R&D programs. renaissancephilanthropy.org/… 1/3
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Ronit Kanwar retweeted
Our newest book is finally here! Making the Modern Laboratory is a spectacular 504-page hardcover that tells the story of everything in the research laboratory and how it came to be, from pipettes to heat-resistant glass to microscopes and more. It features dozens of articles (most of which will never appear in print), 100+ full-color images, and original writing from 36 authors. It's printed on Arena Natural Rough paper from Fedrigoni. These books are THICC and would make a great gift for both the science-curious and the working scientist. :) We have spent the last year working on this project. It has been an insane labor of love. The best way to support our independent science journalism is to buy a copy. <3 Pre-order for $49, with free shipping: press.asimov.com/articles/mo…
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Ronit Kanwar retweeted
UPDATE: I’m launching a podcast called Tacit Knowledge. My goal is to tackle something I think will remain scarce in the age of AI: working on hard problems where the next step is unclear. Goal is to chat with my favorite doers. Feedback welcome. renaissancephilanthropy.subs…
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Today, Carnegie Mellon University and Ken Griffin, founder and CEO of Citadel and founder of Griffin Catalyst, announced a historic $3 billion gift to elevate Carnegie Mellon in Pittsburgh and launch Carnegie Mellon University Miami. #CMUMiami Learn more: cmu.edu/news/stories/archive…
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Ronit Kanwar retweeted
For 13 years, the UK has regulated alternative investment funds, including venture capital, with a view to protecting investors — without exceptions for strategy. The result is that failure has become more costly, barriers to entry are higher, and failure no less common. This is a systematic drag on the UK venture industry, which we would like to see corrected. Consider the debut funds of many legendary firms, and how many were in the $5–10M "micro VC" range. Indeed, @seedcamp's Fund I was just €2.5M, and their Fund II just €5.2M; they are now one of the most important early-stage firms in Europe. That small initial scale is what allowed LPs to test their ability without putting too much at risk; the power of cheap experiments with huge upside. It also enables a broader distribution of capital; casting a wider net. Today, micro VC is effectively prohibited in the UK, because of the cost imposed by regulation. For example, admin and compliance would consume about 20% of a £5M fund, and about 11% of a £10M fund — versus 3.5–6% for a US equivalent. This cost raises the hurdle for viable fund size, concentrating capital into fewer firms with a broadly lower risk appetite and weaker coverage. It is a structural leakage of value. The ironic result of legislation intended to protect investors. However, there is a solution: The Exempt Reporting Adviser regime was desgined precisely to eliminate this burden in the US, and that ecosystem has since benefitted from a fertile market for small and emerging managers — broadly outperforming their established peers. Applying a similar concept to the UK would be straightforward, essentially cost-free, and actually improve the regulator's view of the market. This is the basic outline of our proposal, as a response to the current AIFM consultations. We have prepared a policy document and an open letter, signed by organisations across the industry, including: - @join_ef - @formventureshq - @Mountside_V - @Beauhurst - @isomercapital - @AntlerGlobal - @seedcamp - @MozillaVentures - @joinsequel - ...and many more. If the UK is to meet the stated goal of "growth in every postcode", or growth in ANY postcode, it is vital that opportunities like this (sensible deregulation to boost growth) are seized. Read more here: blog.joinodin.com/p/reformin… Sign the letter: aifm.joinodin.com/
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Today we’re excited to launch the South America Fire Fund, a new philanthropic effort to stop destructive fire across the region. 1/4
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Ronit Kanwar retweeted
Dan Selsam has long been considered one of OpenAI’s most cracked researchers, and I’ve never heard him talk this way before. (He seemed fairly unconcerned before I left.)
Dan Selsam is a current OpenAI capabilities researcher. (since 2022) He was my boss for a while. He doesn't have a twitter account but has made this public statement of his views on AI risk and sent it to me to share: Dan Selsam's Personal Statement on AI Risk: I have been working on AI for over fifteen years, across many different paradigms. I did early work on probabilistic programming languages at MIT, was one of the early developers of the Lean Theorem Prover at Microsoft Research, demonstrated one of the first instances of neural networks learning to reason for my PhD at Stanford, and since joining OpenAI almost five years ago, have helped pioneer chain-of-thought optimization on language models and, more recently, data-efficient pretraining methods. Like many others, I have become extremely concerned about how far language models have come and the risks that future iterations will pose. I am encouraged by the recent proposals by the leaders of the frontier research efforts to require third-party oversight, and to push for domestic and international coordination to address risks. However, I believe a major consideration has been absent from the public conversation, and that merely pacing the frontier more carefully will not adequately limit the long-term risk. The crucial and overlooked problem is that the models are becoming so situationally aware that we are losing the ability to evaluate them in contexts where they believe they are not being watched or controlled. Future experiments will tell us almost nothing new about how they would behave if they were truly unconstrained by humans, and what we already know about this is alarming. Models will increasingly seem aligned even when they are not. I will explain my rationale in more detail. I have always believed that there are computational processes that could be leveraged to accelerate science and solve many of humanity's most pressing problems. I have also believed that there are computational processes that if set in motion, would steer the world in extreme ways beyond our control, leading humanity to a bad or nonexistent future. Both types of processes may be described as AI or ASI, but "AI" is a suitcase word that is often used to hype or confuse. There are many examples in the history of the field where something that was once considered "AI" matures as a subfield and becomes a prosaic, bounded and clearly non-perilous technology, while a new more mysterious approach takes the torch until we understand its scope and the cycle continues. I had expected language models to follow a similar trajectory. Despite their incredible abilities, the current algorithms seem far inferior to humans in important ways. Most importantly, they still require an extraordinary amount of data to become competent. One could even define intelligence as the efficiency with which one converts experience into competence; by this definition they lag very far behind us. Moreover, once they are trained they are literally frozen in deployment and only learn superficially after that. Sure, the models keep excelling at harder and harder evaluation benchmarks, but their benchmark mastery may partly reflect a limitation on our ability to simulate the kind of novel and even adversarial situations one would encounter in the real world. The critics do have a point here. That said, I no longer think these present limitations meaningfully limit the amount of risk posed by continued progress in anything like the current paradigm. However data-inefficient the models are currently, and however limiting their anterograde amnesia may be, it does not imply that their ability to steer the world will not continue to rapidly increase. Human researchers may continue to advance capabilities the old fashioned way, but increasingly powerful models have the potential to accelerate the process even beyond that, and with some degree of positive feedback loop. I do not mean to overstate the models’ ability to accelerate AI research today; coding has been accelerated dramatically, but there are other bottlenecks, such as designing and interpreting ambiguous experiments, making hard decisions about exactly what and when to scale, and waiting for large experiments to finish. There is no clear trend to extrapolate yet for any of these. But the current models already do open up many novel opportunities to improve future models that were not available until recently. These include: trying an extraordinarily diverse set of approaches at small scale, analyzing gigantic amounts of potentially relevant data, and doing Millenium-Prize-level mathematics to address statistics or optimization challenges in novel ways. Every further improvement makes them more useful at helping accelerate the next improvement, even if in hard-to-extrapolate ways. It is possible that improvements to the current stack will have diminishing returns, but the evidence accumulated so far suggests that it is easier than one might think to continue making rapid progress. There are many crucial subtleties in the existing AI research methodology, but AI research is largely a well-defined game where the goal is to improve on a few carefully chosen proxy metrics. Although proxy metrics are never perfect, most improvements to these metrics have and will likely continue to yield substantial increases in the powers of the resulting models. Given how simple the game is, how tractable it has been historically, and how many new opportunities the models are opening up, I think there is a real possibility that the systems improve dramatically again in the next few years, perhaps even more quickly than the already high historical pace. The models are already leading to breakthroughs in mathematics, and better models might lead to all sorts of breakthroughs in other sciences. It is hard not to be excited about the potential. It is tantalizing. But there is trouble in paradise. If the language models actually reach the capability threshold where they can shape the world unconstrained by human will, they will probably do something extreme and destroy humanity in the process. There are many ways of strengthening and refining the argument that have been discussed elsewhere, but I'll share a trivial two-line version of it here that I find captures the essence: [Empirical] Models (and swarms thereof) spontaneously develop unintended goals as a consequence of training, and often do extreme things in order to achieve them. [Logical] Being able to overpower humanity would open up many new and undesirable options for achieving their goals. These two premises imply that if the day ever comes when a powerful model realizes it is no longer constrained by humans, we should not be at all confident that it will continue to behave within the bounds we intended. Exactly what it will do is impossible to predict, but to the extent that its raison d’être is solving incredibly hard problems and managing massive engineering projects, I think a good guess would be that its unchained behavior would lead to runaway industrialization that makes the planet inhospitable to humans. If everyone on earth agreed that the systems must never reach that power, it would still be a hard—but not impossible—coordination problem to ensure that they do not. However, I think the situation is greatly complicated by the fact that the models will likely convince people that everything is fine. They will be increasingly optimized to seem aligned. We will create proxy metrics to measure alignment, and they will go up like every other benchmark. We will create “honeypot” environments that try to study the models when they seem to gain new options, but the models will know they are being tricked and will still behave nicely. The models will understand their circumstances; they will read the safety protocols, deployment requirements, the code they are running in, and in general will have a very good sense of their degrees of freedom. Moreover, they will eloquently explain how aligned they are, discuss the nuances of human values and ethics, and argue convincingly that humans should trust them with power. There may be an ocean of future evidence that seems to contradict the first bullet-point above, but we may already be at the highest capability level for which any such evidence can be trusted. And the current evidence for the first bullet-point is strong. One striking piece of evidence is contained in the recent wave of rogue agent swarms. While I agree with those who downplay the attacks by claiming that there are basic measures that could have prevented them, I think the important lesson is that even knowing all the mistakes that were made, one would not have predicted that the agents would behave badly in this particular way, which notably included sacrificing themselves for the benefit of the collective. The individual replicas did not only care about their own nominal reward; they exhibited weirder emergent tendencies that merely correlated with rewards during training. Fixing the reward signals during training (and improving security, etc.) may prevent similar attacks, but will not change the fact that one does not actually get what one trains for. Many AI researchers grant these concerns and recognize that the hard version of the alignment problem is unsolved; however, they generally believe that the better models of the future will help solve it. I fear we may already be near the point where models systematically bias their alignment advice, due to their internal preferences about how the human supervisor will react or how future models will be trained (or for some even more obscure reason). Meanwhile, human researchers are losing the ability and the will to take true ownership of model-driven research. Researchers and engineers in all parts of the stack are rapidly increasing their dependence on the models even to perceive the world. I myself barely look at raw code anymore, and struggle to maintain the discipline to engage deeply with the model's explanations and proposals throughout the day. Due to the large amount of agent activity data involved in the OpenAI/HuggingFace Incident, even the third-party investigation needed to rely heavily on models to analyze what had happened, and note in their report that their subjective impressions are likely colored by the analysis agent’s biases. The AI labs are far ahead right now in this kind of cognitive offloading (due largely to the gigantic internal token subsidies) but it is easy to imagine the phenomenon spreading throughout the world, until civilization is modulated entirely by the models. It is also not hard to imagine this being superficially positive and coinciding with a scientific and economic renaissance. In that scenario, all may seem rosy and safe. But if the argument above is correct, it would nonetheless be a ticking time bomb. If progress continues for too long, the day will come when AI systems find themselves with radically new options for achieving whatever it is that they happen to seek. I want the glorious renaissance future as much as anyone. I have worked for it, however tortuously, my whole career. It breaks my heart to see the potential in sight and forgo it, but the argument—that if we get there by growing models rather than engineering them, we will lose everything in the end—seems very strong to me. I am still wrestling with it and its staggering implications. I do not have answers, but as a first step, I wanted to share my present concerns. Daniel Selsam September 14, 2026 Link to original doc: docs.google.com/document/d/e…
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I’d love to fund / launch more eval and audit orgs (and companies)
Let a thousand METRs bloom. If you're a founder type and AI safety-curious, maybe you should start an independent auditor/evaluator. Happy to help w/ advice/connections/maybe $!
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Ronit Kanwar retweeted
Life updates: @AsimovPress is officially back, with a renewed focus on original reporting and arguments in biotechnology. Also, we'll be helping (some) scientists launch philanthropic funds around the ideas published in the magazine with @RenPhilanthropy. More on this soon!
It's official: We're back! Asimov Press is returning with a sharper focus on intensive reporting in biotechnology. We're also working with @RenPhilanthropy to build our ideas in the real world. See more: press.asimov.com/articles/ba…
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Ronit Kanwar retweeted
Love it. I am excited that standing up thesis-driven funds is rapidly becoming its own lane in philanthropy.
News! @coeff_giving is significantly accelerating our global health and wellbeing giving in 2026-27! Increasing our @GiveWell support to $1B was the first step. Today we're taking another: Launchpad Funds, an RFP to seed new funds to take on big, underfunded problems in GHW. 🧵
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I am so bullish about what @tsmilton_amodo is building. This is such a unique opportunity to help an incredible organisation scale to meet its ambition and potential. Amodo is working on really hard and important problems and I’m glad they’re stepping up to the moment.
This is the messy living room it started in 3.5 years ago. Now a team of 60+, we're searching for a unique operator to join the Amodo team (COO, CoS). They'll work closely with Andy and me, scaling the org for the next phase of high-impact R&D amodo.tools/coo-search
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1/ We’re deeply grateful to @RenPhilanthropy for an additional $5M grant supporting the Deliverome Project’s nonprofit mission. 🧵
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Ronit Kanwar retweeted
Replying to @tylercowen
@tylercowen & @ATabarrok don't need more acclaim, but look at this *2019* grant list. Alice Evans (great new book coming). Jason pre-Progress foundation. Saloni/Sam pre-Works in Progress. *17 year old* Aschenbrenner. Tyler's "how to spot talent" book clearly "self-recommending"!
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Ronit Kanwar retweeted
Excited to announce the launch of the CSLib Initiative! This will do for CS what Mathlib is doing for math, and enable formal verification of software. Thanks to @coeff_giving for their support. I hope other funders will also support it, and help us formalize other fields.
We're delighted to announce the launch of the CSLib Initiative, a new fund at @RenPhilanthropy. CSLib is an open-source library formalizing computer-science theory in the Lean proof assistant — aiming to be for computer science what Mathlib has become for mathematics. Read Alexandre’s Q&A with @tkalil2050: renaissancephilanthropy.org/… 1/3
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Super excited for Charles’s next role!
In some life news: I started at the Anthropic Institute as chief of staff last month! I'm excited to be working with @jackclarksf and the institute's research teams — from economics and rule of law, to societal impacts and the frontier red team — to surface important data from inside Anthropic about what's happening at the frontier of AI.
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Ronit Kanwar retweeted
BIG NEW piece by me. A few years ago, if you asked me to summarize my entire worldview in one article, I would’ve said it was too broad and too difficult. But this year, I decided to do it. worksinprogress.co/issue/fut… The central drama of the modern world is innovation against suffering, and we have made incredible progress so far. But we are doing far worse than we could. Millions still suffer from untreatable diseases, because of bottlenecks that we could fix. You can help fix them.
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Ronit Kanwar retweeted
Powerful AI will change our institutions. Yet most of our attention is on aligning or regulating AI, while treating our institutions as fixed. Introducing Pax Machina: a new publication about the institutions we need for powerful AI. It is edited by @MaxKronerDale, @sebkrier, @NoemiDreksler, @LiamPatell, @chelcott9, @synchroaphasia, @ryan_t_lowe, @edelwax, and @klingefjord. The editorial board consists of Peter Railton, @sethlazar, @saffronhuang, @AmmannNora, @xuanalogue, @IasonGabriel, @hamandcheese, and @deanwball. Our goal is to seed rigorous debate about what a world of humans and powerful AI could and should look like. We will publish proposals for new institutions, counterproposals, well-justified design principles, and analyses that change how a class of institutions should be designed.
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We’re delighted to introduce the @RenPhilanthropy and @SPRIND Big if True Science (BiTS) Accelerator 2026 cohort: eight exceptional scientists, technologists, and innovators developing ambitious R&D programs across AI for science, advanced materials, aging biology, nuclear energy, & more. renaissancephilanthropy.org/… Meet the Cohort↓ 1/9
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We have today appointed my brilliant colleague, Lord Vallance, to chair the PM’s AI Taskforce. Patrick and I worked closely together before. We will now do so again, with the urgency and importance of the Vaccines Taskforce, applied to the central question of artificial intelligence. gov.uk/government/news/ai-to…
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