What an incredible start to #PCORI26! 🌟 Today, patients, caregivers, researchers and healthcare leaders came together to exchange ideas, foster meaningful collaboration and explore innovative approaches to advancing patient-centered CER. Looking forward to another day of engaging conversations and fresh perspectives as we continue shaping the future of patient-centered CER.

An evidence review looked at available diagnostic tests and treatment options for children and teens with ADHD. Discover what the research reveals about effective ways to diagnose and treat ADHD — and how this evidence can help inform better care decisions for young people. pcori.me/49o2q4c #PCORI26

🗨️ Patients aren't just AI for the clinical information -- they're tying it to their every day lives. #PCORI26

🗨️ What strikes me every year about the PCORI Annual Meeting is not just the range of experience, expertise, and perspectives represented, but what becomes possible when we come together. The exchanges at this meeting infuse our work with new ideas for learning and improvement – ultimately leading to results from PCORI-funded research that are more relevant and useful. #PCORI26

There's still time to join #PCORI26 happening today and tomorrow online from your home or office! Register for free livestream access to the keynote and plenary sessions and hear conversations exploring important topics in patient-centered CER. pcori.me/4zCMfvu

A recent edition of PCORI's Emerging Health Care Innovation Brief features FDA approval of the first treatment for children with a rare lysosomal storage disorder. The ARPA-H also awarded funding to develop an FDA-authorized clinical agentic AI system for cardiovascular care. Other topics to watch: ◻️ Apitegromab, an antibody designed to treat spinal muscular atrophy Types 2 or 3 ◻️ Sonpiretigene isteparvovec, an investigational gene therapy intended to treat a group of rare, inherited eye disorders that affect the retina Read more: pcori.me/4zwTPHI

Submit Your Nominations for the Methodology Committee Committee members help inform recommendations to PCORI's Board of Governors on methodological standards for patient-centered CER, including priorities for addressing gaps in research methods or their applications. pcori.me/4gc9o0P

A PCORI-funded study looked at whether web-based tools could help families manage their child’s asthma. Researchers compared outcomes for children whose families used a standard web-based tool to track asthma symptoms and attacks, an enhanced version of the tool or no tracking tool. The study found children whose families used either version of the online tool had better asthma symptom control and quality of life. They also missed fewer school days and had fewer ER or hospital visits. Read more: pcori.me/4yWv9Zt

🚨 Deadline Tomorrow: Share Your Input on an Alzheimer’s Disease-Related Systematic Review The input received will help inform the final research questions and help ensure important perspectives are considered as the systematic review moves forward. pcori.me/4rxYEhy

Join #PCORI26 virtually Oct. 19-20 for free livestream access to the meeting's mainstage sessions! Listen to opening remarks, the keynote presentation and plenary discussions exploring important topics in patient-centered CER. Register for the Livestream: pcori.me/4e08Rxs

New Evidence Update: Direct Admission for Pediatric Hospitalizations A PCORI-funded study found children admitted through DA waited longer for an initial assessment but received treatment sooner than children admitted through the ER. The findings provide evidence clinicians can consider when deciding how a child who needs hospitalization should be admitted. Read the Evidence Update: pcori.me/46Ba62c

Seeking Input on Upcoming Alzheimer’s Disease-Related Systematic Review Your feedback can help inform the final review and bring forward questions and perspectives important to patients, caregivers and the broader healthcare community. Submit your input by Wednesday, Oct. 14, at 5 p.m. (ET): pcori.me/4rxYEhy

Last Call To Attend #PCORI26 in Person 📢 Join colleagues from across the healthcare community to explore patient-centered CER, exchange ideas and make connections. Attendees will have opportunities to: ◻️ Explore PCORI’s portfolio of patient-centered CER and related projects ◻️ Hear insights and perspectives from across the healthcare community ◻️ Network with colleagues from across the country Reserve your seat today! pcori.me/4fW2BW0

A PCORI-funded RCT is comparing 2 approaches to help prevent future fractures: 1️⃣ Augmented-Fracture Liaison Service: Patients receive education from a patient navigator and have telehealth appointments with a bone health clinician 2️⃣ Enhanced usual care: Patients receive educational materials encouraging them to follow up with their primary care physicians, who are notified about patients at higher risk, and receive information about guideline-recommended fracture care Learn more: pcori.me/4zfM8Wi

A recent edition of PCORI’s Emerging Health Care Innovation Brief features FDA approval of treatments for locally advanced or metastatic breast cancer and Alexander disease. This issue also highlights FDA approval of a dual-energy catheter device for complex or challenging #AFib. Other developments to watch include 2 FDA approvals for: ◼️ Nipocalimab (Imaavy) ◼️ Rusfertide (Mimrylo) pcori.me/47xNXSB

A breast cancer called ductal carcinoma in situ (DCIS) makes up about 25% of new diagnoses and may or may not turn into invasive cancer. To treat DCIS, women often opt for breast-conserving surgery. During the surgery, their clinicians may remove just the tumors or also remove some lymph nodes to perform biopsies. A PCORI-funded patient-centered CER study compared outcomes for women who did or did not receive biopsies during their surgeries. Women who had the biopsies were more likely to have certain short-term side effects than women who didn’t, as well as long-term swelling. pcori.me/3VVpO5V

Top 5️⃣ Reasons To Attend #PCORI26 1️⃣ The latest in CER 2️⃣ Thought-provoking sessions 3️⃣ Valuable Networking and Connections 4️⃣ Inspiring speakers 5️⃣ Free to attend Register here: pcori.me/4fW2BW0

PCORI released an Evidence Update on treatment options for genitourinary syndrome of menopause (GSM). A review of available research from nearly 70 studies on GSM showed that some treatments may help to improve certain symptoms, while others may not. pcori.me/3TqtaMZ

Today, PCORI brought together maternal health leaders, advocates, and policymakers for a roundtable discussion featuring researchers and community partners from PCORI-funded Maternal Health Partner Projects.

Systematic Review Final Report: Primary Hypofractionated Radiation Therapy for Localized #ProstateCancer A new systematic review final report examines the evidence comparing moderate hypofractionation and ultrahypofractionation with conventional radiation therapy, as well as different dose-fractionation regimens and target volumes. pcori.me/4hS1dYY