@KhodosevichLab

Neuroscience lab @UCPH_BRIC. We study neurodevelopmental disorders, such as schizophrenia, autism and epilepsy. Opinions do not reflect that of UCPH.

 København, Danmark
bric.ku.dk/research-groups/Research/khodosevich-group/
Joined April 2018
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We're saying goodbye to X.com and heading over to @bluesky! 🦋 ✈️ Join us there for the next chapter. See you on the other side!🌄 @ khodosevichlab.bsky.social
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Khodosevich Lab retweeted
Zoltan Molnar@ZoltanMolnar647 Jan 2025
Special Neuroscience Seminars on SCHIZOPHRENIA – Recommended for FHS “Wiring the brain” and MSC in Neuroscience Brain Development modules. Developmental Mechanisms in Schizophrenia talks.ox.ac.uk/talks/id/b4bf… Cellular Models of Schizophrenia talks.ox.ac.uk/talks/id/cbbf…
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The Danish Neuro Single Cell (NeuSiC) platform at BRIC opens for requests in mid-February 2025, offering access to advanced single-cell and spatial omics technologies. Funded by the @lundbeckfonden, it supports all steps from sample prep to data analysis. More info: 🧵
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bric.ku.dk/core-facilities/d…
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🚨 Exciting update! 🚨 We've just preprinted our latest paper: "Single-cell profiling of cortical tubers in tuberous sclerosis complex shows molecular structure preservation and massive reorganization of metabolism." Check the following 🧵: biorxiv.org/content/10.1101/…

Single-cell profiling of cortical tubers in tuberous sclerosis complex shows molecular structure...

Tuberous sclerosis complex (TSC) is a multisystemic genetic disorder associated with loss-of-function mutations in the TSC1 or TSC2 gene, which lead mTOR pathway hyperactivation and epileptogenesis....

biorxiv.org
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7️⃣ Therapeutic Insight: Neuron-specific AMPA receptor signaling, especially auxiliary subunits, could be involved in TSC-related epileptogenesis, presenting a potential target for future therapies.
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Dive into the transcriptomic landscape of TSC with us. 👀 🧬 Kudos to @Frederik_friis and all collaborators. 🎉🎇
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Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Congratulations to @wol_laura for successfully defending her PhD thesis on 'Differential impact of maternal immune activation on cell types in the developing neocortex'. 🐀🧬🧑‍🔬
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The annual 'KoKhos lab' retreat has come to an end after 2 days in Gothenburg, Sweden. 🇸🇪 Lots of hiking, informal scientific discussions and team building sessions. There can't be a better end to the summer than this. ☀️🍹⛰️ Refreshing perspectives on the future themes. 🧘‍♂️
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Hike in the city and botanical garden to comfort the eyes with lush greenery around. 🌲🌿
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Big thanks go to the organizers (right) and the PI (left) who supported such an open and friendly lab environment, prioritising personal growth alongside scientific growth.
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Kokhos lab's annual retreat is about to kickoff. No one except the organizers know where we're headed to!
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Prof Konstantin will discuss the application of single cell and spatial omics in translational research during the Emerging Tech Workshop at ARDD2024 on August 26th.🧬 Promising sessions of bridging basic and translational researches leveraging to drug discovery.💊 #ARDD2024
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