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Lifespan Magazine & The Lifespan Show provide evidence-based information so you can live your longest, healthiest life while supporting medical research 🧬💪

lifespan.com
Joined March 2026
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Could your high-protein diet be working against longevity? Protein helps protect muscle, but eating more isn’t always better for long-term health. Learn about the trade-offs between protein, muscle and lifespan lifespan.com/blogs/magazine/…

The Overlooked Risk of Today’s Protein Obsession

When my brother was in medical school, he took up powerlifting. To my surprise, I enjoyed tagging along to the gym more than I expected. There was something I found very satisfying about lifting...

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Are you or your friends fixated on health? How much is too much? What’s the solution? lifespan.com/blogs/magazine/…

Longevity Fixation Syndrome: When Healthy Habits Go Too Far

One of the most memorable university classes I ever took was a late-afternoon neuroscience course. The professor who taught it was charismatic, blunt, and loved reminding us that no organ works in...

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No blood draw. No scanner. Just a photo of your face and an algorithm. Computers are learning to translate selfies into predictions about what’s happening inside your body. What could go right? What could go wrong? Where can I get tested? lifespan.com/blogs/magazine/…
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Peptides are everywhere, but “peptide therapy” can mean anything from an FDA-approved medicine to an untested vial labeled “For Research Use Only.” What do we actually know about the compounds people are injecting? lifespan.com/blogs/magazine/…
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Swapping blood between young and old mice showed old blood actively suppresses tissue repair in the young
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Read about it ➡️ doi.org/10.1038/ncomms13363

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

Nature Communications - Joining the circulatory system of an old with a young animal has been shown to rejuvenate old tissues. Here the authors describe a comparatively simple blood infusion system...

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Bowhead whales can live for >200 years - longer than any other known mammal on earth! 🐳 Enjoy more science cartoons in Lifespan Magazine: lifespan.com/magazine
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Redundancy is why you're alive today, and fragility is why you won't be, unless you build more of it
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People are living longer than ever. But could the average lifespan really jump by another 10 years? Lifespan Magazine 📚️ lifespan.com/blogs/magazine/…
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Pooling 20.9 million observations across 199 studies: high fitness cuts mortality risk 53% versus low
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Read: doi.org/10.1136/bjsports-202…

Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among...

Objective To examine and summarise evidence from meta-analyses of cohort studies that evaluated the predictive associations between baseline cardiorespiratory fitness (CRF) and health outcomes among...

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Just out: Living longer, but Not Better? lifespan.com/blogs/magazine/…

Living Longer, but Not Better?

The word healthspan has become one of the most popular terms in longevity science. Longevity clinics promise to extend it. Supplement companies claim to protect it. Researchers who study aging,...

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Why are we living longer but not better? Lifespan.com/blogs/magazine/…
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What role can AI play in healthy aging? Learn more from Microsoft’s Chief Medical Officer in an interview with Lifespan Magazine 📚️ lifespan.com/blogs/magazine/…

From Bedside to Cloud: Dr. David Rhew on Using AI to Help Us Age Well

Dr. David Rhew is a physician, researcher, and technologist who has spent his career trying to make healthcare both smarter and more humane. He is currently the Global Chief Medical Officer at...

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A new study found that NAD+ levels in whole blood stay surprisingly stable throughout adulthood. So why are scientists still studying NAD+? Learn more from Lifespan Magazine 📚️ lifespan.com/blogs/magazine/…

Blood NAD+ Levels Tell Us Less Than Many People Think

One of the easiest mistakes in science is to confuse a single measurement with the whole reality. We do it all the time. An investor watches a stock price and forgets that the ticker is not the...

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The scientific truth about peptides: Which ones work? Which ones are hype? Which ones to avoid! youtu.be/3CnKnIXKDoE?is=Bf6a…

Younger Skin with Peptides? | Lifespan with Dr. David Sinclair - S2,...

At Lifespan, our mission is to help you and your loved ones live yo...

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Mice engineered to overexpress klotho lived 20–30% longer with no signs of illness doi.org/10.1126/science.1112…

Suppression of Aging in Mice by the Hormone Klotho

A defect in Klotho gene expression in mice accelerates the degeneration of multiple age-sensitive traits. Here, we show that overexpression of Klotho in mice extends life span. Klotho protein...

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A randomized trial gave middle-aged adults Urolithin A for 4 months. Muscle strength improved ~12%
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Read here: doi.org/10.1016/j.xcrm.2022.…
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Exercise is one of the most reliable ways to protect health as you age. Rapamycin is a closely watched longevity drug. What happens when you combine them? Read more from Lifespan Magazine lifespan.com/blogs/magazine/…

Does Rapamycin Block the Benefits of Exercise?

Many, many miles west of South America lies a small, triangle-shaped island housing hundreds of ancient, giant stone statues. The native name for this island is Rapa Nui and, in 1722, explorers from...

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