Cleveland Clinic MD

A 53-year-old firefighter and EMT was transferred from an outside hospital to identify the underlying cause of his symptoms. He presented with unexplained fevers and night sweats and was found to have bloodstream infection with methicillin-sensitive staphylocuccus aureus, which had spread to infect the valves of his heart. More about the case: cle.clinic/4tnrQrx

Kratom is often marketed as a natural product, but its effects on the body can be complex and potentially harmful. At lower doses, kratom can act as a stimulant. At higher doses, it can cause pain relief and sedation. Its use can also lead to dependence and withdrawal symptoms, making it challenging for physicians to recognize and manage: cle.clinic/485OMCH

The years just before and after menopause are when bone loss can be especially high, but many women don't get screened until they're 65: cle.clinic/487mg3y

A 49-year-old man traveled from Peru after being diagnosed with a large secondary brain tumor more than four decades after surviving childhood medulloblastoma. MRI revealed a six-centimeter meningioma compressing his brain. Within days of arriving, he underwent a successful 12-hour surgery followed by advanced molecular testing, imaging and personalized radiation therapy. He continues to do well with virtual follow-up care from his home in Peru. More about the case: cle.clinic/45JLsMd

A negative trial, but not necessarily the end of the Lp(a) story. Lp(a)HORIZON found no event reduction with pelacarsen in secondary prevention despite substantial Lp(a) lowering: cle.clinic/4BJHbqS

Reducing the risk of pulmonary complications after surgery starts with a thorough preoperative evaluation. From managing chronic lung conditions to assessing sleep apnea and adjusting anesthesia plans, clinicians can take steps to reduce respiratory risks and improve patient outcomes: cle.clinic/4isISBD cle.clinic/4isISBD

A 74-year-old woman presented to the hospital from the podiatry clinic for evaluation of bilateral foot pain and purple toes. She had a history of Janus kinase 2 V617F–positive polycythemia vera, Raynaud syndrome, gastroesophageal reflux disease, prior breast cancer and thyroid cancer, hypertension and deep vein thrombosis and pulmonary embolism. More about the case: cle.clinic/4lIAw8B

Online scams can have serious consequences for older adults, affecting more than just their financial security. Adults aged 60 and older reported more than $7.7 billion in losses to online crime in 2025. Beyond financial harm, these scams can also affect mental health and emotional well-being. Our cybersecurity experts share how a new initiative aims to help caregivers and patients recognize online threats, prevent fraud and protect older adults: cle.clinic/4j2fodO

Difficult nursing shifts can take an emotional toll that lasts long after caregivers leave work. Decompression huddles give nurses five to 10 minutes near the end of their shifts to discuss concerns, recognize successes and support one another. Our nursing leaders explain how these brief check-ins can help reduce burnout, strengthen teamwork and build resilience: cle.clinic/4z7wOLc

A 68-year-old woman with relapsing-remitting multiple sclerosis presented for a psychiatric evaluation with eight months of anxiety, irritable mood and increased energy despite sleeping only one to two hours per night, and sometimes not at all. Mood and behavioral changes are well-documented but often underrecognized complications of MS, particularly when psychiatric symptoms blur the line between neurological disease progression and primary mental illness. More about the case: cle.clinic/4uPGit1

Maternal-fetal medicine physicians Adina Kern-Goldberger and Jennifer L. Bailit review factors associated with stillbirth: cle.clinic/4zEwjsX

Human trafficking can be difficult to recognize in healthcare settings, especially when warning signs don't match common assumptions. A recent study found that ambulatory nurses and other healthcare professionals often lack the training, resources and clear guidance needed to identify and respond to patients who may be experiencing human trafficking: cle.clinic/4kwVsB4

An 18-year-old presented with a firm mass arising from the left ulna, with extraosseous extension and visible swelling from the wrist to the elbow. He has autism spectrum disorder with limited verbal communication, as well as a seizure disorder. More about the case: cle.clinic/3UurBPf

A 35-year-old female presented to our emergency department for severe left ankle pain after sustaining a left closed pilon fracture four weeks earlier. She had open reduction and internal fixation four days after the injury at an outside hospital. Her postoperative course was complicated by wound dehiscence with positive cultures for Enterobacter, which was treated with a wound vac and intravenous antibiotics. More about the case: cle.clinic/4zLltBH

In a recent podcast episode, physical therapists discuss how neurorehabilitation has advanced: cle.clinic/4zsw2t7 cle.clinic/4zsw2t7

A 37-year-old woman with a history of multiple sclerosis treated with long-term B cell-depleting therapy developed progressive cognitive, psychiatric and neurological symptoms. Despite extensive testing, conventional diagnostic studies were largely unrevealing. Further testing identified Potosi virus, a rare mosquito-borne pathogen, as the cause of her neurological decline. Our researchers confirmed the virus as a cause of severe central nervous system infection through postmortem analysis and collaboration with the CDC. More about the case: cle.clinic/4yUFGn1

Osseointegration offers patients with limb loss improved mobility and comfort through bone-anchored prostheses without traditional socket: cle.clinic/4z9rDdK

In acute stroke care, time and distance count. Our new neurological building uses design features like skyways, co-located imaging and more to reduce handoffs and care delays: cle.clinic/4A68Pgb

A 59-year-old with a history of bipolar disorder, HIV, cocaine abuse complicated by non-ischemic dilated cardiomyopathy and seizure disorder was admitted from an outside hospital. The patient presented with concerns for respiratory failure and concern for medication-induced liver injury. On arrival, the patient decompensated with worsening shock and encephalopathy, which required mechanical ventilation. More about the case: cle.clinic/4n6VDRd

Missed diagnosis is a real risk in cardiac sarcoidosis. When should clinicians suspect it, and how can collaborative care and multimodality imaging help get it right? cle.clinic/4sWMAqR