Research group studying liver immunology and gut-liver interactions, acute and chronic liver diseases. #liver #immunology #immunooncology #inflammation

Charite Berlin, CVK
Joined September 2019
🙌 This review summarizes recent findings deciphering the relevance of liver macrophage spatial localization as a phenotypical marker and functional contributor to liver diseases. via dx.doi.org/10.1136/egastro-2… @bmj_company @Tacke_lab @FrontGastro @FrankTacke
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A review paper by Prof Frank Tacke & Dr Adrien Guillot entitled ‘Spatial dimension of macrophage heterogeneity in liver diseases’ via egastroenterology.bmj.com/co…
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Now in the latest Hepatology issue! Thanks to all contributors and collaborators! journals.lww.com/hep/Fulltex… Multiplex immunostaining revealed that accumulation of IBA1+ CD16lo CD163lo macrophages near ductular cells is a hallmark of advanced liver disease (incl. NAFLD, PSC).
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What are the mechanisms of fibrosis across organs and disease etiologies? 💡Our latest review examines the underlying processes and resulting therapeutic opportunities. @ILurje authors.elsevier.com/a/1h7z%…
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Ever wondered why CXCR6+ cells in the liver are important? Check out our latest article showing that loss of CXCR6 exacerbates inflammatory IL17 responses in liver! Hepatic C-X-C chemokine receptor type 6–expressing innate... : Hepatology Communications journals.lww.com/hepcomm/Ful…
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Check-out two recent reviews from our department and collaborators on the diverse roles of immune cells in primary liver cancers! Big-up to #MarleneKohlhepp @Branden_HY_Liu @YeniAit #FouadLafdil #AdrienGuillot @Tacke_lab 📌 frontiersin.org/articles/10.… 📌 sciencedirect.com/science/ar…
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Happy #WomenInScience Day! So greatful for this team of powerhouse woman scientists that slay every single day. Let's keep this going @ILurje @JohannaKusnick and the whole twitter-less bunch @Tacke_lab
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Congrats to our PI #AdrienGuillot advocating for science and research! Hooray for the Franco-German friendship! #GenerationEU @ofaj_dfjw @AllemagneDiplo @EmmanuelMacron @Bundeskanzler
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We are thrilled to announce that the members of our lab Adrien Guillot and @ilurje together with Prof. Fouad Lafdil will edit the Special Issue "Tumor-Associated Macrophages in Primary Liver Cancers and in Premalignant Liver Diseases". We look forward to your submissions!
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Just some of our rising stars (@JohannaKusnick AlixBruneau) having fun presenting their data at the annual meeting of @Ferroptosis2306 #ferroptosis #immunogeniccelldeath #curinglivercancer
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Congratulations @CorneliusEngel7 !
🆕Article in press❕ Combination of G-CSF and a #TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of #ACLF Read it here👉bit.ly/3zdoT36 @CorneliusEngel7 #LiverTwitter
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Our collaboration with Bin Gao’s lab just released in JCI: two distinct histopathological phenotypes based on liver immune phenotyping observed in severe alcoholic hepatitis patients Our multiplex IHC is on the cover @Tacke_lab #AdrienGuillot @NIAAAnews xitter.cf/jclinical…
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#Cover: Distinct histopathological phenotypes of severe alcoholic hepatitis: buff.ly/3yC7q2V Image: multiplex immunofluorescence staining of liver tissue with SAH, revealing a large number of inflammatory cells surrounding hepatocytes @NIAAAnews #Gastroenterology
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Delighted to see our review on immune cell heterogeneity in #NAFLD in the era of multi-omics in press at @JHepatology! Thanks to invaluable contributions from @CancerInflam, @RobSchwabe, @Kubes_Lab, Jochen Hampe and of course @Tacke_lab! #LiverTwitter
🆕Review❕ Immune mechanisms linking metabolic injury to inflammation and #fibrosis in #fattyliverdisease – novel insights into cellular communication circuits By @moritzpeiseler & colleagues Read it here👉bit.ly/3OCHtqR #LiverTwitter
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Our master's student just won a speed lecture award talking about her research studying #ferroptosis in #livercancer. So proud!! Congrats @JohannaKusnick @Tacke_lab @Ferroptosis2306 #BIONNALE #fireuptheliver
Replying to @vfapharma
Starker Auftritt, sagt #vfabio: Johanna Kusnick @ChariteBerlin gewinnt den #BIONNALE #SpeedLectureAward 2022, gesponsert von @HealthCapitalBB und #vfabio @vfapharma.
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