@PacBio

Our mission is to enable the promise of #genomics to better human health by creating the world’s most advanced #sequencing technologies. #PacBio

 Menlo Park, California
pacb.com
Joined May 2009
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PacBio
@PacBioAug 18
Leveling the playing field, one long read at a time. Vega SPRQ-Nx chemistry is now shipping! Bring higher throughput, lower DNA input, shorter run times, and expanded methylation detection to your benchtop. What will you discover? Learn more: bit.ly/4geX8g0
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We’re excited to announce a multi-year collaboration with @verilyhealth! Together, we plan to connect PacBio HiFi sequencing with Verily Pre, combining genomic & clinical data to create AI-ready datasets at scale for biomedical research. Learn more: bit.ly/4i98rX1
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From long reads to new discoveries! 🇸🇪 Join Somar Al-Walai at #LRUA2026 on Mon 2 Nov, 10:50, for the latest from PacBio, including how Revio and Vega are bringing HiFi sequencing to more labs. Want to connect with our team? Book a 1:1 meeting in Uppsala: bit.ly/4rX65Pq
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Repeat expansions. Mosaicism. Methylation. One PCR-free workflow. 🎯 PacBio PureTarget uses HiFi sequencing to characterize challenging genes such as FMR1, C9orf72 & SMN1, capturing repeat length, sequence & methylation without amplification. Read more: bit.ly/4i6hyaZ
Purple promotional graphic featuring a stylized "P" logo in the center with the text "All in One Assay" below. Surrounding the logo are phrases related to genetic analysis, such as "Copy number variation," "Structural variants," "Extreme sequence context," and "Tandem repeats," with examples like TNXB, GBA, CYP21A2, SMN1/2, F8, HBA1/2, RNF17, FAN1, AFT2, RAX, and RPGR. The background consists of abstract, overlapping circles.

ALT Purple promotional graphic featuring a stylized "P" logo in the center with the text "All in One Assay" below. Surrounding the logo are phrases related to genetic analysis, such as "Copy number variation," "Structural variants," "Extreme sequence context," and "Tandem repeats," with examples like TNXB, GBA, CYP21A2, SMN1/2, F8, HBA1/2, RNF17, FAN1, AFT2, RAX, and RPGR. The background consists of abstract, overlapping circles.

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Clinical targeted sequencing is evolving. 🧬 Vega SPRQ-Nx makes HiFi sequencing more accessible with higher data output, lower DNA input & faster runs. Explore applications in repeat expansions, HLA typing & more. Download the HiFi Playbook: bit.ly/4ymyrVp
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New preprint from the Quake lab at @Stanford! 🔬 Using Kinnex on Revio, researchers mapped 203,311 single cells across 26 human tissues, finding 37.6% of transcript structures were novel. Read the preprint: bit.ly/4jh6muf Explore Kinnex 16-fold: bit.ly/4APmLfM
Advertisement for a new preprint from Kinnex, featuring a full-length isoform atlas of 26 human tissues. The text highlights 37.6% of transcript structures as novel, with 854,410 detected in total. It mentions data from 203,311 single cells across 144 cell types. The work was built with the Kinnex single-cell RNA kit and is available on bioRxiv, 2026, not yet peer-reviewed.

ALT Advertisement for a new preprint from Kinnex, featuring a full-length isoform atlas of 26 human tissues. The text highlights 37.6% of transcript structures as novel, with 854,410 detected in total. It mentions data from 203,311 single cells across 144 cell types. The work was built with the Kinnex single-cell RNA kit and is available on bioRxiv, 2026, not yet peer-reviewed.

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Now available! Explore HiFi sequencing for biopharma & biotech R&D. 🔬 Hear from industry experts about applications in drug discovery, gene editing, vector characterization, mRNA & antibody therapeutics, and agricultural research. Register for access: bit.ly/4ypZO0d
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Just one week until #ASHG26 in Montréal! 🇨🇦 Visit #PacBio at booth #605 to meet our scientists, see Revio & Vega in action, and explore how HiFi sequencing is advancing human genomics. Plan your visit and explore our full program: bit.ly/46UmMkY
Image with a pink background featuring bold white text that reads, "1 Week Until ASHG 2026!" Below, smaller text reads, "Connect with us at PacBio booth 605." The bottom part of the image includes a teal wave pattern.

ALT Image with a pink background featuring bold white text that reads, "1 Week Until ASHG 2026!" Below, smaller text reads, "Connect with us at PacBio booth 605." The bottom part of the image includes a teal wave pattern.

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PacBio President and CEO, Mark Van Oene, spoke to @GenomeWeb about our new partnership with @tychobio_ai. TychoBio plans to use PacBio HiFi sequencing on 10,000+ samples to generate data for AI models designed for RNA therapy development. Read more here: bit.ly/4rO7bgc
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All 11 contracted D4Z4 alleles detected with Kivvi using PacBio HiFi data. 🧬 A recent preprint shows how Kivvi characterizes repeat size, sequence, chromosome of origin & methylation in FSHD, with potential for broader genetic research. Read more: bit.ly/4yI2OGi
A visual representation of genomic data aligned in horizontal rows with multiple segments of colored rectangular blocks. The blocks are primarily yellow, with scattered black, brown, and magenta segments. A legend at the bottom indicates the colors: yellow for Reference, black for Variant, brown for Flank, and magenta for Low quality or missing data.

ALT A visual representation of genomic data aligned in horizontal rows with multiple segments of colored rectangular blocks. The blocks are primarily yellow, with scattered black, brown, and magenta segments. A legend at the bottom indicates the colors: yellow for Reference, black for Variant, brown for Flank, and magenta for Low quality or missing data.

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PacBio is heading to Uppsala for #LRUA2026! 🇸🇪 As a Platinum Sponsor, we're excited to connect with researchers exploring long-read sequencing. Visit our booth to learn about Revio, Vega & SPRQ-Nx chemistry. Book a 1:1 meeting with our team: bit.ly/4rX65Pq
Gradient background with text: "LRUA 2026. See you in Uppsala. Discover what’s next in HiFi sequencing. 2-4 November 2026." Logo: PacBio.

ALT Gradient background with text: "LRUA 2026. See you in Uppsala. Discover what’s next in HiFi sequencing. 2-4 November 2026." Logo: PacBio.

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A strong grant proposal starts with the right evidence. 📝 Answer a few quick questions about your research and funding goals to access personalized PacBio grant resources, including publications and benchmarking data. Build your case for funding: bit.ly/4A4ZSEK
PacBio promotional graphic with text: "Get your research funded". Includes an image of a brochure titled "HiFi long-read sequencing" with "PacBio" branding. Background features abstract shapes in pastel colors.

ALT PacBio promotional graphic with text: "Get your research funded". Includes an image of a brochure titled "HiFi long-read sequencing" with "PacBio" branding. Background features abstract shapes in pastel colors.

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5 publications. New discoveries powered by PacBio HiFi sequencing. 🧬 From a 12.1% diagnostic yield in unsolved rare disease cases to a single-cell atlas spanning 26 human tissues, explore the latest research using HiFi & Kinnex sequencing. Read more: bit.ly/4j86Z9m
Image with a gradient purple background featuring the text "Jul–Sep Pubs" on the left. To the right, there are three circular images: the first shows two people sitting close together, the second displays code on a screen, and the third depicts a neon illustration of a brain.

ALT Image with a gradient purple background featuring the text "Jul–Sep Pubs" on the left. To the right, there are three circular images: the first shows two people sitting close together, the second displays code on a screen, and the third depicts a neon illustration of a brain.

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Microbial genomes are compact, but the questions are complex. PacBio HiFi sequencing helps resolve microbial genomes and characterize communities. Vega with SPRQ-Nx makes high-resolution sequencing more scalable. 📖 Download the HiFi Playbook: bit.ly/4hQ097R
An advertisement for the SPRQ-Nx on the Vega system by PacBio. The image features text that reads: "HiFi for microbial: A new guide for sample prep, sequencing, and analysis." It highlights elements like "Workflow examples," "Automation tips," and "Vega SPRQ-Nx overview." There's an image of the Vega device and a printed guide.

ALT An advertisement for the SPRQ-Nx on the Vega system by PacBio. The image features text that reads: "HiFi for microbial: A new guide for sample prep, sequencing, and analysis." It highlights elements like "Workflow examples," "Automation tips," and "Vega SPRQ-Nx overview." There's an image of the Vega device and a printed guide.

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Planning your time at #ASHG26? Add #PacBio booth #605 to your list! Meet our scientists, see Revio & Vega in action, and explore how HiFi sequencing is helping researchers see more of the genome. Explore our full program: bit.ly/46UmMkY
Pink and teal promotional image for ASHG 2026. The text reads: "Connect with us at BOOTH 605, October 20-24, #ASHG26." The bottom displays the PacBio logo.

ALT Pink and teal promotional image for ASHG 2026. The text reads: "Connect with us at BOOTH 605, October 20-24, #ASHG26." The bottom displays the PacBio logo.

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Four meaningful days at the 5th Undiagnosed Hackathon in Singapore! 🇸🇬 140 collaborators from 30+ countries came together to tackle challenging undiagnosed disease cases. PacBio was proud to contribute HiFi whole-genome & RNA sequencing support for selected samples.
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Join us for the first Latin American Virtual Symposium on PacBio HiFi Sequencing! 🧬 Hear from experts about HiFi fundamentals, workflows, genomic applications, real-world use cases & get the chance to ask questions live. Register for free: bit.ly/4z3rGYG
Virtual symposium announcement for the First Latin American Symposium on PacBio HiFi Sequencing. Featured speakers include Wayra Navia from PacBio, Jonas Korlach from PacBio, Alvaro Hernandez from the University of Illinois, Alexandre Aleixo from Instituto Tecnológico Vale, and Gerardo E. Fabian from UNAM. The event is scheduled for October 21 at 7:30 AM PT, 9:30 AM CT, and 10:30 AM ET.

ALT Virtual symposium announcement for the First Latin American Symposium on PacBio HiFi Sequencing. Featured speakers include Wayra Navia from PacBio, Jonas Korlach from PacBio, Alvaro Hernandez from the University of Illinois, Alexandre Aleixo from Instituto Tecnológico Vale, and Gerardo E. Fabian from UNAM. The event is scheduled for October 21 at 7:30 AM PT, 9:30 AM CT, and 10:30 AM ET.

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We’re excited to announce a new collaboration with @tychobio_ai to advance AI-driven RNA therapeutics for rare disease. PacBio HiFi + Kinnex sequencing will generate full-length RNA data from 10,000+ samples to help train AI drug discovery models. 🔗 bit.ly/4AVHK0A
🤖 Made with AI
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Look beyond gene-level expression. New Kinnex prep kits are available now: run full-length RNA on 8-fold for the longest transcripts or 12-fold for throughput. Single-cell moves to 16-fold. Learn more: bit.ly/4APmLfM #PacBio #Kinnex #RNAseq
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#PacBio is headed to ASHG 2026 in Montréal! 🇨🇦 From complex variation to multiomic insights, see how HiFi sequencing is bringing more of the genome into view across human genomics. Discover what we have planned for #ASHG26: bit.ly/46UmMkY
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Congratulations to @SampledLabs on its new five-year VA contract supporting the Million Veteran Program! 👏 With multiple PacBio Revio systems, Sampled is bringing scalable HiFi sequencing to one of the world’s largest research programs of its kind. 🔗 prn.to/4y5klHq
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