@LabLuthi

Neuroscience lab investigating sleep physiology 🔎🧠🌜 @UNIL🇨🇭 Now on https://xitter.cf/t.co/wvcBnb6sKt

wwwfbm.unil.ch/dnf/group/gaining-insight-into-the-roles-of-sleep-for-neuronal-function
Joined January 2020
  • Tweets363
  • Following362
  • Followers848
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SleepLüthiLab retweeted
Inna Slutsky@inna_slutskyApr 12
Given these uncertain times, it’s time to reconnect and come together to discuss all things synapse at grc.org/synaptic-transmissio…. Join us in Italy for an outstanding lineup of speakers! We still have open slots for short talks and late-breaking findings. @of_sagol @SamYoungLab
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@LabLuthi is happy to be part of this collaboration, congrats to all authors and to @tpatriarchi for his leadership in this endeavour!
tommaso patriarchi@tpatriarchiFeb 26
The most sensitive green and red #norepinephrine #sensors engineered to date are out in @naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @ERC_Research @snsf_ch @UZH_en @UZH_IPT doi.org/10.1038/s41592-026-0…

Next-generation multicolor indicators for in vivo imaging of norepinephrine

Nature Methods - Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in...

nature.com
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SleepLüthiLab retweeted
Anita Luthi@anita_luthiFeb 1
👉New Preprint out on brain-wide spatiotemporal signatures of #locuscoeruleus activity fluctuations, combining fiber photometry and fMRI 👈A Conserved Locus Coeruleus fMRI Signature of Brain-State Transitions across Sleep, Anesthesia, and Wakefulness biorxiv.org/content/10.64898…
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SleepLüthiLab retweeted
Anita Luthi@anita_luthi29 Dec 2025
Congrats Antoine, Paul-Antoine and all authors for this landmark study on #infraslow rhythms in reptile #sleep, out in @NatureNeuro today - comments here: thetransmitter.org/sleep/sno…

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Lizard sleep may have more in common with mammalian sleep than was previously thought.

thetransmitter.org
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🤩We’re calling for applications for the Physiological Reviews Editor-in-Chief position! 📅Application deadline: April 30, 2026 🎙️Candidate interviews: Spring 2026 🔗Apply now! ow.ly/OutZ50XKQ76
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Three color fiber photometry !!
Yulong Li Lab@yulonglilab6 Jun 2025
Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine science.org/doi/10.1126/scie…

In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors

Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex...

science.org
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@LabLuthi congratulates @GFoustoukos for the Best Publication Award 2025 from the #SSSSC, the #Swiss Society for #Sleep Research, Sleep Medicine and #Chronobiology. A nice recognition of your outstanding research skills!👏 @fbm-unil.bsky.social @NatureNeuro @natneuro.nature.com
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🧠 Paper alert! My scientific labour of love from my time at the @UKDRI at @ucl is now out in @NeuroCellPress ! Deep-layer 5/6 PV interneurons show early dysfunction in Alzheimer's models in vivo, tied to NPTX2 and GluA4 loss. 🔗 cell.com/neuron/fulltext/S08… 🧵Thread below ⬇️
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SleepLüthiLab retweeted
SleepLüthiLab@LabLuthi8 May 2025
The @LabLuthi thanks #CIBM_ch organizers of the first #EEGResearch day - we enjoyed a very informative event and were glad to participate in a Duo Talk @unil #FBM #neuro
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The @LabLuthi thanks #CIBM_ch organizers of the first #EEGResearch day - we enjoyed a very informative event and were glad to participate in a Duo Talk @unil #FBM #neuro
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Congrats Min from @LabLuthi 👌!
Yuval Nir 💔@LabNir15 Apr 2025
A time window for memory consolidation during NREM sleep revealed by cAMP oscillation: Neuron cell.com/neuron/fulltext/S08…
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Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice: Current Biology cell.com/current-biology/ful…

Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across...

Using a mouse model of altered neurotransmission (Vamp2rlss), Guillaumin et al. show that differences typically observed between vigilance states in neural dynamics and spectral signatures can be...

cell.com
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SleepLüthiLab retweeted
Anita Luthi@anita_luthi17 Mar 2025
👉👉New paper alert from @LabLuthi ! Newly promoted Dr. Cherrad, with @GFoustoukos, @FernandezLmj and others combines stimulation of sensory neurons from the #vagus nerve with #sleep, #heartrate, temperature and #locuscoeruleus recordings @unil #FBM #Neuro
bioRxiv Neuroscience@biorxiv_neursci16 Mar 2025
Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation biorxiv.org/content/10.1101/… #biorxiv_neursci

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus...

Parasympathetic nervous system activity, vital for restorative sleep, is influenced by vagal sensory afferents, but how these shape brain-body correlates of sleep remains open. We investigated this...

biorxiv.org
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Brava Francesca! Presenting for the first time her results on LC photometry-fMRI at an international conference #EMIM2025 🎙️ Always a special moment. More to come soon!
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SleepLüthiLab retweeted
Yuval Nir 💔@LabNir7 Mar 2025
The night’s watch: Exploring how sleep protects against neurodegeneration: Neuron cell.com/neuron/fulltext/S08…

The night’s watch: Exploring how sleep protects against neurodegeneration

Parhizkar and Holtzman discuss how sleep disturbances may serve as both an early indicator and potential driver of neurodegenerative diseases, particularly in Alzheimer’s, while reviewing mechanisms...

cell.com
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Pupil size reveals arousal level fluctuations in human sleep nature.com/articles/s41467-0….
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SleepLüthiLab retweeted
Neuron@NeuroCellPress19 Feb 2025
Here's our latest issue: cell.com/neuron/current The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: cell.com/neuron/fulltext/S08… Cover by Nadia Alzoubi
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SleepLüthiLab retweeted
Yulong Li Lab@yulonglilab19 Jan 2025
Almost all neurons co-release peptides and small transmitters. Thrilled to share our latest research where new GRAB sensor promotes better understanding of the dynamics and molecular regulation between neuropeptide and neurotransmitter release in vivo. nature.com/articles/s41467-0…
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It is an exciting time to be studying the functions of noradrenaline waves and micro-arousals in sleep 🧠💤 Take a look at this brand new review from @anita_luthi and Maiken Nedergaard on the subject
Anita Luthi@anita_luthi13 Jan 2025
Anything but small: Microarousals stand at the crossroad between noradrenaline signaling and key sleep functions: Neuron cell.com/neuron/fulltext/S08…

Anything but small: Microarousals stand at the crossroad between noradrenaline signaling and key...

Clinically, microarousals are mostly pathological sleep disruptions linked to health risks. Neurobiologically, microarousals support the roles of noradrenergic infraslow fluctuations in healthy mouse...

cell.com
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SleepLüthiLab retweeted
Anita Luthi@anita_luthi13 Jan 2025
thetransmitter.org/sleep/fle…

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

thetransmitter.org
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