Professor of #computerscience @Stanford; Co-founder at https://xitter.cf/t.co/hhm1j5wP0f #machinelearning #graphs.

Stanford, CA
Joined August 2007
๐Ÿš€ I'm excited to announce the Stanford Data-Centric AI Workshop 2026 (aka the Stanford Graph Learning Workshop), happening Tuesday, November 3, 2026 at @Stanford University (with online livestream). Free registration! Submit a poster. ๐Ÿ“ This year's workshop will spotlight three fast-moving frontiers in data-centric AI: -- AI Foundations โ€” Making frontier models fast and scalable -- AI for Science and Biology โ€” Agents and foundation models across the scales of biology -- Relational and Tabular Foundation Models โ€” Learning directly on the structured data that runs the world We're bringing together Stanford researchers and industry partners for a full day of research talks, case studies, and collaborative discussion. Whether you're working in industry, academia, or startup land, there will be something to spark your curiosity and drive your work forward. ๐Ÿ” Want to share your work? Our Call for Posters and Demos is also open now. โœ… Register now (free): snap.stanford.edu/graphlearnโ€ฆ ๐Ÿ“… Save the date: Nov 3, 2026
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Exciting work by @WUFang40615703 on how models can become better based on their own feedback.
๐—–๐—ฎ๐—ป ๐—ฎ ๐—บ๐˜‚๐—น๐˜๐—ถ๐—บ๐—ผ๐—ฑ๐—ฎ๐—น ๐—บ๐—ผ๐—ฑ๐—ฒ๐—น ๐—ฏ๐—ฒ๐—ฐ๐—ผ๐—บ๐—ฒ ๐—ฎ ๐—ฏ๐—ฒ๐˜๐˜๐—ฒ๐—ฟ ๐—ถ๐—บ๐—ฎ๐—ด๐—ฒ ๐—ด๐—ฒ๐—ป๐—ฒ๐—ฟ๐—ฎ๐˜๐—ผ๐—ฟ ๐—ฏ๐˜† ๐—น๐—ฒ๐—ฎ๐—ฟ๐—ป๐—ถ๐—ป๐—ด ๐—ณ๐—ฟ๐—ผ๐—บ ๐—ถ๐˜๐˜€ ๐—ผ๐˜„๐—ป ๐—ณ๐—ฒ๐—ฒ๐—ฑ๐—ฏ๐—ฎ๐—ฐ๐—ธ? ๐Ÿš€ Excited to share ๐—จ๐—ป๐—ถ๐—˜๐˜ƒ๐—ผ-๐—ฉ๐—Ÿ, our new work on on-policy self-distillation for multimodal model self-improvement! The motivation is simple: as generation and understanding come together in multimodal systems, models can provide feedback on their own outputs. Can that feedback become a useful training signalโ€”turning their ability to evaluate into improvements in generation? ๐Ÿ“ˆ ๐—ง๐—ต๐—ฒ ๐—ฟ๐—ฒ๐˜€๐˜‚๐—น๐˜๐˜€ Building on Qwen-image-2512, UniEvo-VL improves: โ€ข GenEval: ๐Ÿฌ.๐Ÿณ๐Ÿฐ๐Ÿณ โ†’ ๐Ÿฌ.๐Ÿด๐Ÿฌ๐Ÿด โ€ข GenEval2 Soft-TIFA: ๐Ÿฏ๐Ÿฎ.๐Ÿต๐Ÿณ โ†’ ๐Ÿฏ๐Ÿฑ.๐Ÿฑ๐Ÿฏ These gains show the potential of learning from self-generated feedback. But the boundaries are just as interesting. ๐Ÿ” ๐—ช๐—ต๐—ฎ๐˜ ๐˜€๐—ฒ๐˜๐˜€ ๐˜๐—ต๐—ฒ ๐—ฐ๐—ฒ๐—ถ๐—น๐—ถ๐—ป๐—ด? Experiments with stronger external critics suggest room for further improvement. This raises a central challenge: producing feedback is only the beginning. That feedback must be reliable enough to guide learning. Understanding what makes a good critic matters for building a better generator. ๐Ÿ” ๐——๐—ผ๐—ฒ๐˜€ ๐—ถ๐—บ๐—ฝ๐—ฟ๐—ผ๐˜ƒ๐—ฒ๐—บ๐—ฒ๐—ป๐˜ ๐˜๐—ฟ๐—ฎ๐—ป๐˜€๐—ณ๐—ฒ๐—ฟ ๐—ฎ๐—ฐ๐—ฟ๐—ผ๐˜€๐˜€ ๐˜๐—ฎ๐˜€๐—ธ๐˜€? Not uniformly. Text-rendering results remain mixed, even as the overall generation benchmarks improve. Progress on one benchmark does not mean every capability improves alongside itโ€”a useful boundary to understand when studying self-improving systems. For me, the broader research question is: ๐—ช๐—ต๐—ฒ๐—ป ๐—ถ๐˜€ ๐—ฎ ๐—บ๐—ผ๐—ฑ๐—ฒ๐—นโ€™๐˜€ ๐—ผ๐˜„๐—ป ๐—ณ๐—ฒ๐—ฒ๐—ฑ๐—ฏ๐—ฎ๐—ฐ๐—ธ ๐—ฟ๐—ฒ๐—น๐—ถ๐—ฎ๐—ฏ๐—น๐—ฒ ๐—ฒ๐—ป๐—ผ๐˜‚๐—ด๐—ต ๐˜๐—ผ ๐—ต๐—ฒ๐—น๐—ฝ ๐—ถ๐˜ ๐—ถ๐—บ๐—ฝ๐—ฟ๐—ผ๐˜ƒ๐—ฒ? UniEvo-VL takes a step toward answering this question for multimodal generation, exploring both the opportunities and the limitations. Grateful to all my collaborators for making this work possible! If youโ€™re working on self-distillation, multimodal post-training, or self-improving models, Iโ€™d love to hear your perspective. ๐Ÿ“„ Paper: arxiv.org/abs/2609.38721 ๐Ÿค— Hugging Face: huggingface.co/papers/2609.3โ€ฆ If you find the work interesting, a repost or an upvote on Hugging Face would help more researchers discover it. Thanks for your support! ๐Ÿ™ #UniEvoVL #SelfDistillation #MultimodalAI #ImageGeneration #PostTraining
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Iโ€™m very excited to share @nvidia Kumo Tabular, a new family of foundation models for tabular data. Kumo Tabular establishes the new Pareto frontier across the entire accuracyโ€“inference-time tradeoff. Just as importantly, we are releasing it openly: open weights, open-source software, and a permissive license for commercial use. HuggingFace: huggingface.co/nvidia/Kumo-Tโ€ฆ GitHub: github.com/NVIDIA/structuredโ€ฆ
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Not that long ago, building a machine learning system meant carefully designing features, choosing a model architecture, training it from scratch, tuning hyperparameters, and repeating this process for every new problem. Then foundation models changed how we think about text, images, and increasingly other modalities: pretrain once, then adapt to new tasks through context. The same transition is now happening for structured data. With Kumo Tabular, you provide a table with labeled examples and rows you want predictions for. The model produces predictions in a single forward pass --โ€” with no task-specific training, no fine-tuning, and no feature engineering. What makes this especially exciting to me is that this is not just a new model, but part of a rapidly growing research ecosystem around tabular foundation models. There is tremendous innovation happening across academia and industry in architectures, synthetic pretraining, in-context learning, evaluation, and efficient inference. NVIDIA wants to be an active part of that ecosystem โ€”-- contributing research, releasing models openly, and building infrastructure that helps the community push the field forward. There are several aspects of the work I find particularly interesting. ** The models are pretrained entirely on synthetic tables generated from structural causal models, allowing us to expose them to enormous diversity without training on customer data or benchmark datasets. The largest model sees more than 100 million synthetic tables during pretraining. ** The resulting models are both accurate and efficient. Across major tabular benchmarks, Kumo Tabular improves upon strong existing approaches while requiring no per-dataset training. On TabArena, for example, Kumo Tabular Large sits on the accuracyโ€“speed Pareto frontier and is 17ร— faster at prediction than LimiX-2. To me, the bigger story is the direction ML is moving: from hand-built models for individual tasks to pretrained models that learn broad representations of a domain and can solve new problems from context. We have seen this transformation in language and vision. It is exciting to see it now reaching the enormous world of structured data. Huge congratulations to the team โ€” and to the broader tabular foundation model research community whose ideas and work are making this new paradigm possible. Weโ€™re excited to contribute, learn, and help build this ecosystem together.
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Introducing CUDA Rust! CUDA Rust lets you write GPU kernels natively in Rust, not just launch them from it. Two paths: cuda-oxide for SIMT kernels compiled to PTX, and cutile-rs for Tile-based programming on stable Rust. Both can catch aliasing errors at compile time. Technical blog: nvda.ws/4hm1bHS
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Excited to see this out! Relational learning needs strong benchmarks, standardized evaluation, and easy ways to bring methods to real-world relational data.
Weโ€™re happy to announce our first release in relational learning at Prior Labs, continuing our commitment to open science. We open-source three pieces of software that we expect to accelerate research in the field towards meaningful, real-world impact. First and foremost, we release ๐—ฅ๐—ฒ๐—น๐—”๐—ฟ๐—ฒ๐—ป๐—ฎ-ฮฑ: a unified framework for running and comparing baselines on RelBench v1 tasks. Based on learnings from tabular benchmarks like TabArena, we are standardizing data loading, evaluation protocols, tuning regimes, and adding support for systems with custom tuning. We also open-source ๐—ง๐—ฎ๐—ฏ๐—ฃ๐—™๐—ก-๐—ฅ๐—ฒ๐—น: our relational harness for TabPFN-3. We initialize the (living) RelArena-ฮฑ leaderboard with TabPFN-Rel and a comprehensive set of baselines. The rankings at the time of release are: โ€ข ๐—ง๐—ฎ๐—ฏ๐—ฃ๐—™๐—ก-๐—ฅ๐—ฒ๐—น is the No. 1 model submission โ€ข ๐—ฅ๐—ง-๐—ฃ๐—น๐˜‚๐—ฅ๐—ฒ๐—น is the No. 1 system submission Last but not least, we open-source an alpha version of the ๐—ฅ๐—ฒ๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐—ฎ๐—น ๐—ฃ๐—ฟ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—œ๐—ป๐˜๐—ฒ๐—ฟ๐—ณ๐—ฎ๐—ฐ๐—ฒ (๐—ฅ๐—ฃ๐—œ): enabling you to easily specify prediction tasks on your own relational database and then run any RelArena-ฮฑ model, like TabPFN-Rel, in a few lines of code, all bundled as a simple PyPI package. โ€ข Read the full model report: arxiv.org/abs/2608.16319 โ€ข GitHub repository (give us a โญ๏ธ): github.com/PriorLabs/relarenโ€ฆ โ€ข Announcement: priorlabs.ai/blog-posts/intrโ€ฆ โ€ข Docs: docs.priorlabs.ai/capabilitiโ€ฆ Thanks to the contributions from: @adrihayler, @KNfloege, @AlanArazi1536, @_rishabhranjan_, @jure, @LennartPurucker, @FrankRHutter & @noahholl
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Fun conversation with @ItaiYanai on @nightsciencepod about what happens when AI starts doing science: agents that find patterns, generate hypotheses, and try to falsify them with more data. We also got into taste, judgment, and where human scientists still matter most. open.spotify.com/episode/0pyโ€ฆ podcasts.apple.com/us/podcasโ€ฆ
How would you let the LLM dream? [...] In a sense, to replay things, organize them, think about them so that tomorrow when we wake up, our thoughts are more organized than just input-output-input-output. โ€“Jure Leskovec, Stanford Professor, @jure
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Exciting milestone for @KexinHuang5 and the @phylo_bio team. Putting AI scientist systems directly in the hands of discovery scientists is where the next big gains in biomedical AI will come from.
Today, we're delighted to announce Phylo's partnership with Ono Pharma to deploy Biomni Lab to its discovery scientists. At Phylo, we believe agentic AI will fundamentally change how new medicines are discovered. Ono is a global leader in innovative drug discovery with a rich history of scientific leadership. Together, we will embed AI agents throughout the research process, accelerating the path from complex questions to scientific discoveries. We're honored to partner with Ono on this transformation. Read more: phylo.bio/blog/ono-partnershโ€ฆ
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Excited to share that our Universal Cell Embedding (UCE) paper is published in @Nature ! Single-cell RNA sequencing data gives us an unprecedented look into the diversity of cell biology, but analysis has often been limited to the specific dataset or atlas that was collected. nature.com/articles/s41586-0โ€ฆ
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UCE connects molecular and cellular scales of biology. Genes are more than just columns in an expression matrix: in UCE, they are encoded according to the proteins they produce, using ESM, embedding novel species not seen during training, across 100Ms of years of evolution.
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Jure Leskovec retweeted
Today, we're excited to share that Biomni is published in @ScienceMagazine. Biomedical research is still fragmented, manual, and difficult to scale. In this work, we introduce Biomni - the first general-purpose biomedical AI agent with an integrated biology environment that can reason, plan, and execute end-to-end scientific workflows. We show that, with the right environment and harness, AI can automate large-scale omics analyses, orchestrate laboratory robotics, optimize molecular properties, and even train new AI models for biology. We also introduce a reinforcement learning recipe for continually improving biomedical AI agents, enabling open-source models to achieve frontier-level performance. It's surreal to look back. We started the Biomni project in early 2024, when agentic AI was still nascent. It is exciting to see tens of thousands of biologists collaborating with agents every day to accelerate science. Try Biomni: biomni.phylo.bio Read more: science.org/doi/10.1126/scieโ€ฆ This work is not possible without this truly inter-disciplinary team: @serena2z @hcwww_ @YuanhaoQ Minta Lu, Ryan Li, @yusufroohani Lin Qiu @shiyi_c98 Gavin Junze Di @rickwierenga @kavi_deniz Sherry @TianweiShe Shruti Jennefer Xin Zhou @MWheelerMD Jon Bernstein @MengdiWang10 @PengHeAtlas @zhou_jingtian @SnyderShot @lecong Aviv Regev @jure @StanfordAILab @genentech @phylo_bio @arcinstitute @UW @berkeley_ai @RetroBio_ @tamarindbio @Princeton @UCSF
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Modern multimodal models aren't a single decode loop anymore; they're composite. M* is one runtime that serves them all, and it matches or beats every specialized system: up to 2.7ร— on omni TTS, 12.5ร— on world-model rollouts. Learn more here: ai.stanford.edu/blog/mstar/
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Jure Leskovec retweeted
Cancer diagnosis is informed by cellular annotations of histopathology, but assays are expensive or rely on manual annotations. At #ICML2026, we present SpatialWhisperer, a trimodal model that zero-shot annotates cell types in histopathology images. ๐Ÿงต๐Ÿ‘‡
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Jure Leskovec retweeted
๐ŸŽ‰๐ŸŽ‰ PluRel will be presented at #ICML2026 ๐ŸŽ‰๐ŸŽ‰ Date: Tue, Jul 7, 2026 โ€ข 10:30 AM โ€“ 12:15 PM KST Location: HALL A #2715 by co-author: @_rishabhranjan_ ! Also checkout our latest website for interactive visualizations, access to code, models and data: star-project.stanford.edu/plโ€ฆ
Relational Foundation Models face a scaling problem: diverse training datasets are rarely public due to privacy constraints ๐Ÿ”’. ๐Ÿš€ We are excited to introduce "PluRel": a framework that synthesizes diverse multi-table relational databases from scratch, unlocking scaling laws for RFMs. ๐Ÿงต Kudos to the amazing collaborators at @StanfordAILab @Kumo_ai_team , and @SAP : @_rishabhranjan_ @VHudovernik @vijaypradwi @johanneshoffart @guestrin @jure
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Jure Leskovec retweeted
Excited to share a research collaboration with @ScaleAILabs - we rigorously evaluate bio agents on different models across 82 drug discovery tasks - interesting findings include: (1) know-how/environment >>> models (2) different LLMs have different strength - highlighting a need for model-routing for biology agents:
We get this question a lot: "Which model is best for drug discovery?" Our new benchmark announced today with @ScaleAILabs, DrugDiscoveryBench (82 tasks from working drug discovery scientists, run on Biomni Open Source Environment), has a clear answer: the model matters far less than what you build around it. ๐Ÿงต3 key takeaways โ†’
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Jure Leskovec retweeted
Biology doesn't happen in one place. We're bringing Biomni Lab from your browser to your phone, your desktop, and your agent of choice via MCP. Biomni comes with you wherever your work happens. Sign up for the closed beta (Mobile and Desktop): forms.gle/JbB4vV4GdaZcaLU19 Use Biomni MCP today: mcp.phylo.bio/mcp Blog: phylo.bio/blog/biomni-everywโ€ฆ
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