@JAMANetworkOpen

JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

 Chicago, IL
jamanetworkopen.com
Joined April 2017
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5.2KMedia
📊 Among more than 1 million children in US families with mixed citizenship status, noncitizen children were more often uninsured than citizen children, indicating unequal insurance access within the same household. ja.ma/4ssFUk1
Table 2 comparing characteristics of noncitizen and citizen children in mixed-status US families, including mean children per family, race and ethnicity breakdown, and health insurance types (private, public, uninsured).

ALT Table 2 comparing characteristics of noncitizen and citizen children in mixed-status US families, including mean children per family, race and ethnicity breakdown, and health insurance types (private, public, uninsured).

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In children born preterm, the association between epigenetic aging and #Neurodevelopment was context dependent, with severe brain injury modifying the association between epigenetic age acceleration and motor outcomes. ja.ma/4ynIGIo
A scatter plot showing motor score at 3 y versus epigenetic age difference in weeks. It compares two groups: 'No severe brain injury: adjusted fit' (blue circles/line) and 'Severe brain injury: adjusted fit' (orange triangles/dashed line).

ALT A scatter plot showing motor score at 3 y versus epigenetic age difference in weeks. It compares two groups: 'No severe brain injury: adjusted fit' (blue circles/line) and 'Severe brain injury: adjusted fit' (orange triangles/dashed line).

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📊 Among adolescents and young adults with #Depression, misuse of prescription psychotherapeutic drugs and prescription drug use disorder were more common than among peers without depression. ja.ma/4zzGgr7
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Among older primary care patients, an electronic health record-integrated #FallPrevention tool with tailored #Exercise recommendations was associated with a modest but significant reduction in falls and fall-related injuries vs usual care. ja.ma/4Ba5eix
A JAMA Network Open infographic summarizing an RCT on fall prevention in primary care. It outlines the population (11,945 patients, mean age 77.1), intervention, settings, and findings showing a significant reduction in falls for the eSTEPS CDS group.

ALT A JAMA Network Open infographic summarizing an RCT on fall prevention in primary care. It outlines the population (11,945 patients, mean age 77.1), intervention, settings, and findings showing a significant reduction in falls for the eSTEPS CDS group.

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#CervicalCancer screening rates increased across all groups from 2019-2024. However, disparities persisted, particularly among American Indian, Alaska Native, Native Hawaiian, and Pacific Islander patients, along with those in the Western and Southern US. ja.ma/4Baf0B1
A screenshot of a JAMA Network Open article titled \"Cervical Cancer Screening Rates by Race and Ethnicity, Age, Language, and Census Region,\" authored by Yunbo Xie, MPH, and others, published October 16, 2026.

ALT A screenshot of a JAMA Network Open article titled \"Cervical Cancer Screening Rates by Race and Ethnicity, Age, Language, and Census Region,\" authored by Yunbo Xie, MPH, and others, published October 16, 2026.

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National #Homicide mortality among women of reproductive age declined after the COVID-19 surge, but post-Dobbs trends diverged, with less favorable trajectories in states with sustained abortion bans vs states without such bans. ja.ma/4zCvArV
A line graph showing monthly homicide deaths from 2016 to 2025. It highlights a COVID-19 surge in April 2020, a postsurge recovery in January 2022, and a post-Dobbs period starting July 2022, indicating trajectory and statistical changes.

ALT A line graph showing monthly homicide deaths from 2016 to 2025. It highlights a COVID-19 surge in April 2020, a postsurge recovery in January 2022, and a post-Dobbs period starting July 2022, indicating trajectory and statistical changes.

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A national study of Icelandic women found technology-facilitated sexual violence and other coercive sexual acts highly prevalent, particularly among younger women, indicating that action is needed to respond to the evolving landscape of sexual violence. ja.ma/4i3bvnx
Two line graphs showing lifetime prevalence in 2024 (%) by age group (23-34 to 65-74). Graph A details technology-facilitated sexual violence experiences, showing higher rates in younger groups. Graph B details other coercive sexual acts.

ALT Two line graphs showing lifetime prevalence in 2024 (%) by age group (23-34 to 65-74). Graph A details technology-facilitated sexual violence experiences, showing higher rates in younger groups. Graph B details other coercive sexual acts.

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🩸 Among adults with acute nontraumatic coma undergoing prehospital rapid sequence induction, point-of-care #GFAP testing showed high diagnostic accuracy for intracranial hemorrhage and may help guide triage to specialist care. ja.ma/3Wd0Fnv
A ROC curve graph with 'False-positive rate' on the x-axis and 'True-positive rate' on the y-axis, both ranging from 0 to 1. The curve shows high performance with an AUC of 0.94, accompanied by a shaded confidence interval.

ALT A ROC curve graph with 'False-positive rate' on the x-axis and 'True-positive rate' on the y-axis, both ranging from 0 to 1. The curve shows high performance with an AUC of 0.94, accompanied by a shaded confidence interval.

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In Veterans with #COPD and/or asthma, #AATD testing and augmentation therapy were low. Further disparities were associated with older adults, those actively using tobacco, patients from minoritized racial and ethnic groups, and those farther from care. ja.ma/4jjzwZJ
A JAMA Network Open article titled 'Disparities in a1-Antrypsin Deficiency Testing and Treatment in US Adults' by Arianne K. Baldomero, MD, MS, et al., published online on October 15, 2026.

ALT A JAMA Network Open article titled 'Disparities in a1-Antrypsin Deficiency Testing and Treatment in US Adults' by Arianne K. Baldomero, MD, MS, et al., published online on October 15, 2026.

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In metastatic androgen pathway modulator-resistant #ProstateCancer, outcomes with Lu-177 prostate-specific membrane antigen were broadly consistent across treatment lines and taxane sequencing groups. ja.ma/3TYl3Ic
Two Kaplan-Meier survival curves comparing OS probability (A) and TTNT probability (B) based on taxane timing relative to Lu-177 PSMA therapy: before, after, or never. Each graph displays probability percentages against time in months with risk tables.

ALT Two Kaplan-Meier survival curves comparing OS probability (A) and TTNT probability (B) based on taxane timing relative to Lu-177 PSMA therapy: before, after, or never. Each graph displays probability percentages against time in months with risk tables.

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📊 Higher #UltraprocessedFoods intake in middle-aged adults was associated with greater body fat, greater visceral adipose tissue, and higher odds of vascular brain injury on #MRI, but not with differences in cognitive performance. ja.ma/4s54APj
A screenshot of a JAMA Network Open article titled \"Ultraprocessed Food Intake and Adiposity, Vascular Brain Injury, and Cognition in Middle-Aged Adults,\" authored by Russell J. de Souza et al., and published online October 15, 2026.

ALT A screenshot of a JAMA Network Open article titled \"Ultraprocessed Food Intake and Adiposity, Vascular Brain Injury, and Cognition in Middle-Aged Adults,\" authored by Russell J. de Souza et al., and published online October 15, 2026.

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🫀 In Danish adults aged 30 years or older, socioeconomic inequality in major adverse cardiovascular events persisted over 4 decades. Rates fell across all income groups, but lower income remained associated with higher #CardiovascularDisease burden. ja.ma/4s6JxLW
Two line graphs labeled A (Males) and B (Females) showing the age-standardized incidence rate ratio of MACE from 1988 to 2023 across income quartiles (1 vs 4, 2 vs 4, 3 vs 4), with shaded confidence intervals.

ALT Two line graphs labeled A (Males) and B (Females) showing the age-standardized incidence rate ratio of MACE from 1988 to 2023 across income quartiles (1 vs 4, 2 vs 4, 3 vs 4), with shaded confidence intervals.

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📊 Among patients with #RectalCancer treated with total neoadjuvant treatment, watch-and-wait was associated with better long-term bowel function, social and physical functioning, role functioning, and global health status vs total mesorectal excision. ja.ma/4jtICmR
Three horizontal bar charts show adjusted mean differences for QOL items (A), QOL scales (B), and Wexner score (C). Most QOL items show negative differences, while scales mostly show positive differences, ranging from -25 to 25.

ALT Three horizontal bar charts show adjusted mean differences for QOL items (A), QOL scales (B), and Wexner score (C). Most QOL items show negative differences, while scales mostly show positive differences, ranging from -25 to 25.

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📊 Among #BreastCancer survivors receiving aromatase inhibitors, carbon dioxide laser therapy did not improve sexual function, dyspareunia, or vaginal health more than sham treatment at 12 months when both groups received nonhormonal first-line therapy. ja.ma/4yQW2xQ
An infographic summarizing a JAMA Network Open study on laser therapy for sexual health in 84 breast cancer survivors. Findings show fractional CO2 laser therapy did not significantly improve sexual function at 12 months compared to sham laser.

ALT An infographic summarizing a JAMA Network Open study on laser therapy for sexual health in 84 breast cancer survivors. Findings show fractional CO2 laser therapy did not significantly improve sexual function at 12 months compared to sham laser.

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JAMA Network Open retweeted
JAMA
@JAMA_currentOct 15
The JAMA Network announces @JAMA_AI_, a new peer-reviewed online journal dedicated to the science of artificial intelligence, digital health, and emerging technologies that are transforming medicine and health care. Led by inaugural Editor in Chief Roy H. Perlis, MD, MSc, JAMA AI will publish research spanning the full spectrum of AI in health care, from advances in AI capabilities and clinical applications to rigorous evaluation and real-world implementation. The journal will begin accepting submissions in early 2027. ➡️ Learn more and sign up for updates: ja.ma/4z26fYg
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🎉 Heading to #LIVES2026? Check out our page created for attendees. Find recent articles and podcasts, and get information For Authors on @JAMA_current, and @JAMAInternalMed, @JAMAPediatrics, and @JAMANetworkOpen. ja.ma/4zn7OzZ
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Among adults eligible for hereditary cancer #GeneticTesting, a digital intervention increased testing uptake by 6 months and telephone health coaching increased uptake by 12 months vs usual care. ja.ma/3TSiPKC
RCT on digital & coaching interventions to boost cancer genetic testing uptake. 793 patients (320M, 458F, median age 64) randomized. Bar chart shows Digital Intervention led to highest GT completion (~7%), then Genetic Health Coaching (~5.5%), and Usual Care (~2%). Digital odds ratio: 3.88.

ALT RCT on digital & coaching interventions to boost cancer genetic testing uptake. 793 patients (320M, 458F, median age 64) randomized. Bar chart shows Digital Intervention led to highest GT completion (~7%), then Genetic Health Coaching (~5.5%), and Usual Care (~2%). Digital odds ratio: 3.88.

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For adults initiating #Buprenorphine during hospitalization, a patient navigation and #mHealth incentive intervention was feasible to deliver and highly rated, with similar outpatient linkage as usual care in this pilot trial. ja.ma/4yLkAZ7
JAMA Network Open RCT summary: Mobile health intervention for OUD care linkage in 40 hospitalized patients (33M, 7F, mean 43.4y). 20 received incentivized support, 20 usual care. Bar chart shows ~11 vs ~10 linked to care. Risk ratio 1.10 (0.61-1.99), no significant difference.

ALT JAMA Network Open RCT summary: Mobile health intervention for OUD care linkage in 40 hospitalized patients (33M, 7F, mean 43.4y). 20 received incentivized support, 20 usual care. Bar chart shows ~11 vs ~10 linked to care. Risk ratio 1.10 (0.61-1.99), no significant difference.

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Among adults receiving recommended care for #Diabetes, #Hypertension, or both, out-of-pocket costs were higher in high-deductible health plans than in non–high-deductible health plans. ja.ma/47gTZao
Line graph shows OOP cost difference ($) vs. OOP cost decile for 6 groups: Individual/Family diabetes & hypertension, Individual/Family diabetes no hypertension, & Individual/Family hypertension only. All lines generally rise to a peak around 0.80 decile, then fall. Magenta line peaks highest.

ALT Line graph shows OOP cost difference ($) vs. OOP cost decile for 6 groups: Individual/Family diabetes & hypertension, Individual/Family diabetes no hypertension, & Individual/Family hypertension only. All lines generally rise to a peak around 0.80 decile, then fall. Magenta line peaks highest.

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Among patients with acute #Stroke due to medium vessel occlusion, perfusion mismatch profiles were not associated with 90-day functional outcomes and did not modify the effect of endovascular thrombectomy. ja.ma/47gTSvu
Four charts show estimated probabilities of excellent/good functional outcomes for acute MeVO stroke. Compared are 'Usual care' (dark grey) and 'EVT and usual care' (orange) across perfusion mismatch volume/ratio. 'Usual care' consistently shows higher outcome probabilities.

ALT Four charts show estimated probabilities of excellent/good functional outcomes for acute MeVO stroke. Compared are 'Usual care' (dark grey) and 'EVT and usual care' (orange) across perfusion mismatch volume/ratio. 'Usual care' consistently shows higher outcome probabilities.

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