In JBC press| TRPML1 loss disrupts lysosome–mitochondria homeostasis and sensitizes MDA-MB-231 triple-negative breast cancer cells to chemotherapy.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| EAG1 channel is a central regulator of tumor growth and metastasis in A549 non-small cell lung cancer cells.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
Day 3 of #TalesFromTheLab 🦇 | How do vampire bats keep blood flowing? Their saliva contains a clot-dissolving enzyme that fibrin stimulates 45,000-fold.
ow.ly/gBBX50ZZ8Wx #JBiolChem #ASBMBJournals
Day 1 of #TalesFromTheLab 🎃 | Fireflies don't waste their glow: this JBC study found an enzyme that recycles the spent light-emitting molecule back into fresh fuel.
ow.ly/RYXY50ZZ7H3 #JBiolChem #ASBMBJournals
In JBC press| Stress-induced helicase DHX36 controls neuroinflammation.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| Regulation of Müller glial reprogramming by the stress response protein REDD1 and its limitations in preventing retinal degeneration.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| Vps1 and select autophagic machinery are required for coenzyme Q uptake and trafficking to mitochondria.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| A prostate cancer–specific super-enhancer at 1q42.3 regulates the CAPN2 and KRT19.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| Discovery and characterization of Chondroitinase A with specificity for 4-O-sulfated N-acetylgalactosamine in Chondroitin sulfate/Dermatan sulfate.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| Activation-induced cytidine deaminase sustains glycolytic flux through MYST1 acetyltransferase-dependent lactylation in hepatocellular carcinoma.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| Calcium-dependent proteolysis of the chimeric androglobin reveals altered localization of its isolated globin domain.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
In JBC press| Color-tuned Channelrhodopsins for Multiwavelength Optogenetics.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
Journal of Biological Chemistry retweeted
Since we first shared this one, it made the cover. 🎉 Our SCA48 paper is on the cover of @jbiolchem, with CHIP drawn as the dimer it forms (PDB 2C2L) above the Purkinje neurons that degenerate in the disease, artwork by @fenguita 🧬🧠
1/New paper in @jbiolchem! 🧬 Why do patients with spinocerebellar ataxia type 48 (SCA48) look so different from each other? We find the answer is written into the CHIP protein itself — and it depends on which domain is mutated. 🔗 jbc.org/article/S0021-9258(2…
New in JBC press| Molecular mechanism of augmentation of oncogenic activity of MYC by TAF2 in HCC.
Learn more:
jbc.org/article/S0021-9258(2…
New in JBC press| Medulloblastoma-associated mutations in the RNA helicase DDX3X/DED1 cause defects in the translational response to TORC1 inhibition.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
New in JBC press| The razABCD regulatory island links azalomycin F biosynthesis in Streptomyces iranensis to orsellinic acid production in the fungus Aspergillus nidulans.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
New in JBC press| Biochemical, Bioluminescence and Bioreporter Properties of Functionally Improved Firefly Luciferases#.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
New in JBC press| Dynamic reprogramming and A-to-I RNA editing in neutrophils in response to tumor induction.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
New in JBC press| Agmatine as the initiating substrate for aspartate semialdehyde-dependent bacterial spermidine biosynthesis.
Learn more:
jbc.org/article/S0021-9258(2…
#JBiolChem
New in JBC press| Calmodulin acts as a selective switch in FGF12A-mediated regulation of the cardiac sodium channel Nav1.5.
Learn more:
jbc.org/article/S0021-9258(2…






















