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Updated preprint up - direct supplementation with the metabolic cofactor Coenzyme A reverses macrophage immunosuppression + promotes pro-inflammatory & anti-microbial macrophage phenotypes via positive influence on CoA-dependent glucose metabolism (1/x) biorxiv.org/content/10.1101/… – at Berkeley, CA
Greg Timblin retweeted
Weird stat: No team in college football history has defeated BYU a year after turning down a Pop-Tarts Bowl invite to play BYU the previous season
Greg Timblin retweeted
Every piece of this article is perfect, Princeton PhD, chemical engineering (the most boring and career-oriented subject), he builds electronics in his spare time, and then applies for more jobs in his breaks.
If this guy can’t get a job, none of you will, ever again!
Greg Timblin retweeted
Every single person you meet in your daily life is fighting a hidden battle that you know nothing about
Send them a Zoom meeting link for an 8 AM call on Monday morning to finish them off
"We found that stereoprobes reacting with C124 in the nucleotide exchange factor GRPEL1 disrupt interactions with the mitochondrial HSP70 chaperone HSPA9/mortalin, leading to impairments in mitochondrial protein import and mitophagy induction. "
nature.com/articles/s41589-0… – at Berkeley, CA
Greg Timblin retweeted
The year is 2040. 64 teams make the CFP. The entire SEC gets an autobid. The committee leaves out 12-1 JMU for 4-8 Purdue. You cant complain cause Flock owns everything. Notre Dame misses the playoffs and opts to not play in the Palantir Bowl sponsored by Kalshi. Life is good.
Greg Timblin retweeted
🫀 Exercise is medicine!
2026 ACC: Biggest benefits occur when inactive people start moving. Combine aerobic and resistance training.
Exercise should be prescribed, not just recommended.
jacc.org/doi/10.1016/j.jacc.…
Greg Timblin retweeted
VCs will watch a college football locker room speech and think it's exactly what the founder of a B2B expense management startup needs to hear.
"...antibodies to IL1RA induce resorption, inflammation & vascular malperfusion in pregnant mice. These findings identify a term pregnancy humoral immune program...including anti-IL1RA, which may have direct pathogenic consequences."
nature.com/articles/s41590-0… – at Berkeley, CA
"Anakinra, a synthetic form of IL-1RA, has been used for 2 decades to treat inflammatory diseases including RA...the results suggest that the drug could be a way to prevent preterm births, by putting the brakes back on IL-1, preventing inflammation & preterm uterine contractions" – at Berkeley, CA
Researchers have uncovered a hidden immune signal that may trigger some preterm births, offering a possible way to predict and mitigate risk earlier. The discovery also points to an existing anti-inflammatory drug as a possible preventive treatment. ucsfh.org/4yjWFyP
Greg Timblin retweeted
Researchers have uncovered a hidden immune signal that may trigger some preterm births, offering a possible way to predict and mitigate risk earlier. The discovery also points to an existing anti-inflammatory drug as a possible preventive treatment. ucsfh.org/4yjWFyP























